# OmniInfer: System-Wide Acceleration Techniques for Optimizing LLM Serving Throughput and Latency

arXiv: https://arxiv.org/abs/2511.22481 · HTML: https://mlsanity.com/paper/2511.22481/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Serving systems and request scheduling, one of 12 directions in Efficient LLM inference and serving.
- Builds on 38 of its 45 references that are in the map.
- First posted on arXiv 27 Nov 2025.

## Placed in

- Efficient LLM inference and serving / [Serving systems and request scheduling](https://mlsanity.com/inference/serving-systems-and-request-scheduling/)

## Builds on (most cited first, 30 of 38)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Training Verifiers to Solve Math Word Problems](https://mlsanity.com/paper/2110.14168/) (2021)
- [Qwen3 Technical Report](https://mlsanity.com/paper/2505.09388/) (2025)
- [DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learning](https://mlsanity.com/paper/2501.12948/) (2025)
- [Efficient Memory Management for Large Language Model Serving with PagedAttention](https://mlsanity.com/paper/2309.06180/) (2023)
- [Measuring Mathematical Problem Solving With the MATH Dataset](https://mlsanity.com/paper/2103.03874/) (2021)
- [Toolformer: Language Models Can Teach Themselves to Use Tools](https://mlsanity.com/paper/2302.04761/) (2023)
- [Switch Transformers: Scaling to Trillion Parameter Models with Simple and Efficient Sparsity](https://mlsanity.com/paper/2101.03961/) (2021)
- [Efficient Streaming Language Models with Attention Sinks](https://mlsanity.com/paper/2309.17453/) (2023)
- [MMLU-Pro: A More Robust and Challenging Multi-Task Language Understanding Benchmark](https://mlsanity.com/paper/2406.01574/) (2024)
- [gpt-oss-120b & gpt-oss-20b Model Card](https://mlsanity.com/paper/2508.10925/) (2025)
- [SGLang: Efficient Execution of Structured Language Model Programs](https://mlsanity.com/paper/2312.07104/) (2023)
- [DeepSeek-V2: A Strong, Economical, and Efficient Mixture-of-Experts Language Model](https://mlsanity.com/paper/2405.04434/) (2024)
- [SnapKV: LLM Knows What You are Looking for Before Generation](https://mlsanity.com/paper/2404.14469/) (2024)
- [H2O: Heavy-Hitter Oracle for Efficient Generative Inference of Large Language Models](https://mlsanity.com/paper/2306.14048/) (2023)
- [Mixture-of-Experts with Expert Choice Routing](https://mlsanity.com/paper/2202.09368/) (2022)
- [DistServe: Disaggregating Prefill and Decoding for Goodput-optimized Large Language Model Serving](https://mlsanity.com/paper/2401.09670/) (2024)
- [Kimi K2: Open Agentic Intelligence](https://mlsanity.com/paper/2507.20534/) (2025)
- [Splitwise: Efficient generative LLM inference using phase splitting](https://mlsanity.com/paper/2311.18677/) (2023)
- [Taming Throughput-Latency Tradeoff in LLM Inference with Sarathi-Serve](https://mlsanity.com/paper/2403.02310/) (2024)
- [DeepSpeed-MoE: Advancing Mixture-of-Experts Inference and Training to Power Next-Generation AI Scale](https://mlsanity.com/paper/2201.05596/) (2022)
- [LongBench v2: Towards Deeper Understanding and Reasoning on Realistic Long-context Multitasks](https://mlsanity.com/paper/2412.15204/) (2024)
- [DuoAttention: Efficient Long-Context LLM Inference with Retrieval and Streaming Heads](https://mlsanity.com/paper/2410.10819/) (2024)
- [A Survey on Efficient Inference for Large Language Models](https://mlsanity.com/paper/2404.14294/) (2024)
- [Tutel: Adaptive Mixture-of-Experts at Scale](https://mlsanity.com/paper/2206.03382/) (2022)
- [Mooncake: A KVCache-centric Disaggregated Architecture for LLM Serving](https://mlsanity.com/paper/2407.00079/) (2024)
- [DynamoLLM: Designing LLM Inference Clusters for Performance and Energy Efficiency](https://mlsanity.com/paper/2408.00741/) (2024)
- [Efficient LLM Scheduling by Learning to Rank](https://mlsanity.com/paper/2408.15792/) (2024)
- [Preble: Efficient Distributed Prompt Scheduling for LLM Serving](https://mlsanity.com/paper/2407.00023/) (2024)
- [MemServe: Context Caching for Disaggregated LLM Serving with Elastic Memory Pool](https://mlsanity.com/paper/2406.17565/) (2024)

## Abstract (arXiv)

Large Language Models drive a wide range of modern AI applications but impose substantial challenges on large-scale serving systems due to intensive computation, strict latency constraints, and throughput bottlenecks. We introduce OmniInfer, a unified system-level acceleration framework designed to maximize end-to-end serving efficiency through fine-grained optimization of expert placement, cache compression, and scheduling. OmniInfer integrates three complementary components: OmniPlacement for load-aware Mixture-of-Experts scheduling, OmniAttn for sparse attention acceleration, and OmniProxy for disaggregation-aware request scheduling. Built atop vLLM, OmniInfer delivers system-wide performance gains through adaptive resource disaggregation, efficient sparsity exploitation, and global coordination across prefill and decode phases. Evaluated on DeepSeek-R1 within a 10-node Ascend 910C cluster, OmniInfer achieves 616 QPM, where the unified framework reduces TPOT by 36%, and the superimposition of OmniProxy further slashes TTFT by 38%. The project is open-sourced at [this https URL](https://gitee.com/omniai/omniinfer).