# Lost in Time? A Meta-Learning Framework for Time-Shift-Tolerant Physiological Signal Transformation

arXiv: https://arxiv.org/abs/2511.21500 · HTML: https://mlsanity.com/paper/2511.21500/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 13 of its 44 references that are in the map.
- First posted on arXiv 26 Nov 2025.

## Builds on (most cited first, 13 of 13)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [mixup: Beyond Empirical Risk Minimization](https://mlsanity.com/paper/1710.09412/) (2017)
- [Co-teaching: Robust Training of Deep Neural Networks with Extremely Noisy Labels](https://mlsanity.com/paper/1804.06872/) (2018)
- [DivideMix: Learning with Noisy Labels as Semi-supervised Learning](https://mlsanity.com/paper/2002.07394/) (2020)
- [InceptionTime: Finding AlexNet for Time Series Classification](https://mlsanity.com/paper/1909.04939/) (2019)
- [Meta Label Correction for Noisy Label Learning](https://mlsanity.com/paper/1911.03809/) (2019)
- [ProMix: Combating Label Noise via Maximizing Clean Sample Utility](https://mlsanity.com/paper/2207.10276/) (2022)
- [Learning to Purify Noisy Labels via Meta Soft Label Corrector](https://mlsanity.com/paper/2008.00627/) (2020)
- [CardioGAN: Attentive Generative Adversarial Network with Dual Discriminators for Synthesis of ECG from PPG](https://mlsanity.com/paper/2010.00104/) (2020)
- [PPG2ABP: Translating Photoplethysmogram (PPG) Signals to Arterial Blood Pressure (ABP) Waveforms using Fully Convolutional Neural Networks](https://mlsanity.com/paper/2005.01669/) (2020)
- [Performer: A Novel PPG-to-ECG Reconstruction Transformer for a Digital Biomarker of Cardiovascular Disease Detection](https://mlsanity.com/paper/2204.11795/) (2022)
- [IncepSE: Leveraging InceptionTime's performance with Squeeze and Excitation mechanism in ECG analysis](https://mlsanity.com/paper/2312.09445/) (2023)

## Built on by (most cited first, 2 of 2)

- [HypeMed: Enhancing Medication Recommendations with Hypergraph-Based Patient Relationships](https://mlsanity.com/paper/2603.18459/) (2026)
- [FinInvest-GTCN: Explainable Graph-Temporal-Causal Modeling for Risk-Aware Investment Decision Optimization](https://mlsanity.com/paper/2606.28933/) (2026)

## Abstract (arXiv)

Translating non-invasive signals such as photoplethysmography (PPG) and ballistocardiography (BCG) into clinically meaningful signals like arterial blood pressure (ABP) is vital for continuous, low-cost healthcare monitoring. However, temporal misalignment in multimodal signal transformation impairs transformation accuracy, especially in capturing critical features like ABP peaks. Conventional synchronization methods often rely on strong similarity assumptions or manual tuning, while existing Learning with Noisy Labels (LNL) approaches are ineffective under time-shifted supervision, either discarding excessive data or failing to correct label shifts. To address this challenge, we propose ShiftSyncNet, a meta-learning-based bi-level optimization framework that automatically mitigates performance degradation due to time misalignment. It comprises a transformation network (TransNet) and a time-shift correction network (SyncNet), where SyncNet learns time offsets between training pairs and applies Fourier phase shifts to align supervision signals. Experiments on one real-world industrial dataset and two public datasets show that ShiftSyncNet outperforms strong baselines by 9.4%, 6.0%, and 12.8%, respectively. The results highlight its effectiveness in correcting time shifts, improving label quality, and enhancing transformation accuracy across diverse misalignment scenarios, pointing toward a unified direction for addressing temporal inconsistencies in multimodal physiological transformation.