# Adversarial Multi-Task Learning for Liver Tumor Segmentation, Dynamic Enhancement Regression, and Classification

arXiv: https://arxiv.org/abs/2511.20793 · HTML: https://mlsanity.com/paper/2511.20793/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 17 of its 38 references that are in the map.
- First posted on arXiv 25 Nov 2025.

## Builds on (most cited first, 17 of 17)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [Non-local Neural Networks](https://mlsanity.com/paper/1711.07971/) (2017)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [Spatial Transformer Networks](https://mlsanity.com/paper/1506.02025/) (2015)
- [ResUNet++: An Advanced Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1911.07067/) (2019)
- [Enhanced U-Net: A Feature Enhancement Network for Polyp Segmentation](https://mlsanity.com/paper/2105.00999/) (2021)
- [Modified U-Net (mU-Net) with Incorporation of Object-Dependent High Level Features for Improved Liver and Liver-Tumor Segmentation in CT Images](https://mlsanity.com/paper/1911.00140/) (2019)
- [H-DenseUNet: Hybrid Densely Connected UNet for Liver and Tumor Segmentation from CT Volumes](https://mlsanity.com/paper/1709.07330/) (2017)
- [Edge-aware Multi-task Network for Integrating Quantification Segmentation and Uncertainty Prediction of Liver Tumor on Multi-modality Non-contrast MRI](https://mlsanity.com/paper/2307.01798/) (2023)
- [T-CACE: A Time-Conditioned Autoregressive Contrast Enhancement Multi-Task Framework for Contrast-Free Liver MRI Synthesis, Segmentation, and Diagnosis](https://mlsanity.com/paper/2508.09919/) (2025)

## Built on by (most cited first, 1 of 1)

- [MATS: A novel multi-modality multi-task learning framework for 3D perception in autonomous driving](https://mlsanity.com/paper/2607.24224/) (2026)

## Abstract (arXiv)

Liver tumor segmentation, dynamic enhancement regression, and classification are critical for clinical assessment and diagnosis. However, no prior work has attempted to achieve these tasks simultaneously in an end-to-end framework, primarily due to the lack of an effective framework that captures inter-task relevance for mutual improvement and the absence of a mechanism to extract dynamic MRI information effectively. To address these challenges, we propose the Multi-Task Interaction adversarial learning Network (MTI-Net), a novel integrated framework designed to tackle these tasks simultaneously. MTI-Net incorporates Multi-domain Information Entropy Fusion (MdIEF), which utilizes entropy-aware, high-frequency spectral information to effectively integrate features from both frequency and spectral domains, enhancing the extraction and utilization of dynamic MRI data. The network also introduces a task interaction module that establishes higher-order consistency between segmentation and regression, thus fostering inter-task synergy and improving overall performance. Additionally, we designed a novel task-driven discriminator (TDD) to capture internal high-order relationships between tasks. For dynamic MRI information extraction, we employ a shallow Transformer network to perform positional encoding, which captures the relationships within dynamic MRI sequences. In experiments on a dataset of 238 subjects, MTI-Net demonstrates high performance across multiple tasks, indicating its strong potential for assisting in the clinical assessment of liver tumors. The code is available at: https://github.com/xiaojiao929/MTI-Net.