# A Systematic Analysis of Large Language Models with RAG-enabled Dynamic Prompting for Medical Error Detection and Correction

arXiv: https://arxiv.org/abs/2511.19858 · HTML: https://mlsanity.com/paper/2511.19858/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 21 of its 42 references that are in the map.
- First posted on arXiv 25 Nov 2025.

## Builds on (most cited first, 21 of 21)

- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Sentence-BERT: Sentence Embeddings using Siamese BERT-Networks](https://mlsanity.com/paper/1908.10084/) (2019)
- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [PaLM: Scaling Language Modeling with Pathways](https://mlsanity.com/paper/2204.02311/) (2022)
- [Billion-scale similarity search with GPUs](https://mlsanity.com/paper/1702.08734/) (2017)
- [Survey of Hallucination in Natural Language Generation](https://mlsanity.com/paper/2202.03629/) (2022)
- [BioBERT: a pre-trained biomedical language representation model for biomedical text mining](https://mlsanity.com/paper/1901.08746/) (2019)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [BLEURT: Learning Robust Metrics for Text Generation](https://mlsanity.com/paper/2004.04696/) (2020)
- [Publicly Available Clinical BERT Embeddings](https://mlsanity.com/paper/1904.03323/) (2019)
- [Fact or Fiction: Verifying Scientific Claims](https://mlsanity.com/paper/2004.14974/) (2020)
- [BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Mining](https://mlsanity.com/paper/2210.10341/) (2022)
- [Self-Alignment Pretraining for Biomedical Entity Representations](https://mlsanity.com/paper/2010.11784/) (2020)
- [Explainable Automated Fact-Checking for Public Health Claims](https://mlsanity.com/paper/2010.09926/) (2020)
- [CoAID: COVID-19 Healthcare Misinformation Dataset](https://mlsanity.com/paper/2006.00885/) (2020)
- [MEDEC: A Benchmark for Medical Error Detection and Correction in Clinical Notes](https://mlsanity.com/paper/2412.19260/) (2024)
- [ReCOVery: A Multimodal Repository for COVID-19 News Credibility Research](https://mlsanity.com/paper/2006.05557/) (2020)

## Abstract (arXiv)

Objective: Clinical documentation contains factual, diagnostic, and management errors that can compromise patient safety. Large language models (LLMs) may help detect and correct such errors, but their behavior under different prompting strategies remains unclear. We evaluate zero-shot prompting, static prompting with random exemplars (SPR), and retrieval-augmented dynamic prompting (RDP) for three subtasks of medical error processing: error flag detection, error sentence detection, and error correction. Methods: Using the MEDEC dataset, we evaluated nine instruction-tuned LLMs (GPT, Claude, Gemini, and OpenAI o-series models). We measured performance using accuracy, recall, false-positive rate (FPR), and an aggregate score of ROUGE-1, BLEURT, and BERTScore for error correction. We also analyzed example outputs to identify failure modes and differences between LLM and clinician reasoning. Results: Zero-shot prompting showed low recall in both detection tasks, often missing abbreviation-heavy or atypical errors. SPR improved recall but increased FPR. Across all nine LLMs, RDP reduced FPR by about 15 percent, improved recall by 5 to 10 percent in error sentence detection, and generated more contextually accurate corrections. Conclusion: Across diverse LLMs, RDP outperforms zero-shot and SPR prompting. Using retrieved exemplars improves detection accuracy, reduces false positives, and enhances the reliability of medical error correction.