# Uncertainty of Network Topology with Applications to Out-of-Distribution Detection

arXiv: https://arxiv.org/abs/2511.18813 · HTML: https://mlsanity.com/paper/2511.18813/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 14 of its 28 references that are in the map.
- First posted on arXiv 24 Nov 2025.

## Builds on (most cited first, 14 of 14)

- [Dropout as a Bayesian Approximation: Representing Model Uncertainty in Deep Learning](https://mlsanity.com/paper/1506.02142/) (2015)
- [Fashion-MNIST: a Novel Image Dataset for Benchmarking Machine Learning Algorithms](https://mlsanity.com/paper/1708.07747/) (2017)
- [Simple and Scalable Predictive Uncertainty Estimation using Deep Ensembles](https://mlsanity.com/paper/1612.01474/) (2016)
- [Aleatoric and Epistemic Uncertainty in Machine Learning: An Introduction to Concepts and Methods](https://mlsanity.com/paper/1910.09457/) (2019)
- [A Review of Uncertainty Quantification in Deep Learning: Techniques, Applications and Challenges](https://mlsanity.com/paper/2011.06225/) (2020)
- [Generalized Out-of-Distribution Detection: A Survey](https://mlsanity.com/paper/2110.11334/) (2021)
- [Black Box Variational Inference](https://mlsanity.com/paper/1401.0118/) (2013)
- [Persistence Images: A Stable Vector Representation of Persistent Homology](https://mlsanity.com/paper/1507.06217/) (2015)
- [A Kernelized Stein Discrepancy for Goodness-of-fit Tests and Model Evaluation](https://mlsanity.com/paper/1602.03253/) (2016)
- [Uncertainty Quantification and Deep Ensembles](https://mlsanity.com/paper/2007.08792/) (2020)
- [Topology of deep neural networks](https://mlsanity.com/paper/2004.06093/) (2020)
- [Neural Persistence: A Complexity Measure for Deep Neural Networks Using Algebraic Topology](https://mlsanity.com/paper/1812.09764/) (2018)
- [Topological Uncertainty: Monitoring trained neural networks through persistence of activation graphs](https://mlsanity.com/paper/2105.04404/) (2021)
- [Variable Selection with Rigorous Uncertainty Quantification using Deep Bayesian Neural Networks: Posterior Concentration and Bernstein-von Mises Phenomenon](https://mlsanity.com/paper/1912.01189/) (2019)

## Abstract (arXiv)

Persistent homology (PH) is a crucial concept in computational topology, providing a multiscale topological description of a space. It is particularly significant in topological data analysis, which aims to make statistical inference from a topological perspective. In this work, we introduce a new topological summary for Bayesian neural networks, termed the predictive topological uncertainty (pTU). The proposed pTU measures the uncertainty in the interaction between the model and the inputs. It provides insights from the model perspective: if two samples interact with a model in a similar way, then they are considered identically distributed. We also show that the pTU is insensitive to the model architecture. As an application, pTU is used to solve the out-of-distribution (OOD) detection problem, which is critical to ensure model reliability. Failure to detect OOD input can lead to incorrect and unreliable predictions. To address this issue, we propose a significance test for OOD based on the pTU, providing a statistical framework for this issue. The effectiveness of the framework is validated through various experiments, in terms of its statistical power, sensitivity, and robustness.