# A novel approach to classification of ECG arrhythmia types with latent ODEs

arXiv: https://arxiv.org/abs/2511.16933 · HTML: https://mlsanity.com/paper/2511.16933/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 5 of its 23 references that are in the map.
- First posted on arXiv 21 Nov 2025.

## Builds on (most cited first, 5 of 5)

- [UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction](https://mlsanity.com/paper/1802.03426/) (2018)
- [On Neural Differential Equations](https://mlsanity.com/paper/2202.02435/) (2022)
- [Automatic diagnosis of the 12-lead ECG using a deep neural network](https://mlsanity.com/paper/1904.01949/) (2019)
- [Equinox: neural networks in JAX via callable PyTrees and filtered transformations](https://mlsanity.com/paper/2111.00254/) (2021)
- [Path-minimizing Latent ODEs for improved extrapolation and inference](https://mlsanity.com/paper/2410.08923/) (2024)

## Abstract (arXiv)

12-lead ECGs with high sampling frequency are the clinical gold standard for arrhythmia detection, but their short-term, spot-check nature often misses intermittent events. Wearable ECGs enable long-term monitoring but suffer from irregular, lower sampling frequencies due to battery constraints, making morphology analysis challenging. We present an end-to-end classification pipeline to address these issues. We train a latent ODE to model continuous ECG waveforms and create robust feature vectors from high-frequency single-channel signals. We construct three latent vectors per waveform via downsampling the initial 360 Hz ECG to 90 Hz and 45 Hz. We then use a gradient boosted tree to classify these vectors and test robustness across frequencies. Performance shows minimal degradation, with macro-averaged AUC-ROC values of 0.984, 0.978, and 0.976 at 360 Hz, 90 Hz, and 45 Hz, respectively, suggesting a way to sidestep the trade-off between signal fidelity and battery life. This enables smaller wearables, promoting long-term monitoring of cardiac health.