# EchoAgent: Guideline-Centric Reasoning Agent for Echocardiography Measurement and Interpretation

arXiv: https://arxiv.org/abs/2511.13948 · HTML: https://mlsanity.com/paper/2511.13948/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 6 of its 24 references that are in the map.
- First posted on arXiv 17 Nov 2025.

## Builds on (most cited first, 6 of 6)

- [HuggingGPT: Solving AI Tasks with ChatGPT and its Friends in Hugging Face](https://mlsanity.com/paper/2303.17580/) (2023)
- [EchoPrime: A Multi-Video View-Informed Vision-Language Model for Comprehensive Echocardiography Interpretation](https://mlsanity.com/paper/2410.09704/) (2024)
- [EchoApex: A General-Purpose Vision Foundation Model for Echocardiography](https://mlsanity.com/paper/2410.11092/) (2024)
- [Multi-step retrieval and reasoning improves radiology question answering with large language models](https://mlsanity.com/paper/2508.00743/) (2025)
- [EchoVLM: Dynamic Mixture-of-Experts Vision-Language Model for Universal Ultrasound Intelligence](https://mlsanity.com/paper/2509.14977/) (2025)
- [EHR-MCP: Real-world Evaluation of Clinical Information Retrieval by Large Language Models via Model Context Protocol](https://mlsanity.com/paper/2509.15957/) (2025)

## Built on by (most cited first, 1 of 1)

- [Echo-CoPilot: A Multiple-Perspective Agentic Framework for Reliable Echocardiography Interpretation](https://mlsanity.com/paper/2512.09944/) (2025)

## Abstract (arXiv)

Purpose: Echocardiographic interpretation requires video-level reasoning and guideline-based measurement analysis, which current deep learning models for cardiac ultrasound do not support. We present EchoAgent, a framework that enables structured, interpretable automation for this domain. Methods: EchoAgent orchestrates specialized vision tools under Large Language Model (LLM) control to perform temporal localization, spatial measurement, and clinical interpretation. A key contribution is a measurement-feasibility prediction model that determines whether anatomical structures are reliably measurable in each frame, enabling autonomous tool selection. We curated a benchmark of diverse, clinically validated video-query pairs for evaluation. Results: EchoAgent achieves accurate, interpretable results despite added complexity of spatiotemporal video analysis. Outputs are grounded in visual evidence and clinical guidelines, supporting transparency and traceability. Conclusion: This work demonstrates the feasibility of agentic, guideline-aligned reasoning for echocardiographic video analysis, enabled by task-specific tools and full video-level automation. EchoAgent sets a new direction for trustworthy AI in cardiac ultrasound.