# MediRound: Multi-Round Entity-Level Reasoning Segmentation in Medical Images

arXiv: https://arxiv.org/abs/2511.12110 · HTML: https://mlsanity.com/paper/2511.12110/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 36 of its 53 references that are in the map.
- First posted on arXiv 15 Nov 2025.

## Builds on (most cited first, 30 of 36)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Visual Instruction Tuning](https://mlsanity.com/paper/2304.08485/) (2023)
- [Qwen Technical Report](https://mlsanity.com/paper/2309.16609/) (2023)
- [Grounding DINO: Marrying DINO with Grounded Pre-Training for Open-Set Object Detection](https://mlsanity.com/paper/2303.05499/) (2023)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [LISA: Reasoning Segmentation via Large Language Model](https://mlsanity.com/paper/2308.00692/) (2023)
- [The Medical Segmentation Decathlon](https://mlsanity.com/paper/2106.05735/) (2021)
- [The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classification](https://mlsanity.com/paper/2107.02314/) (2021)
- [Image Segmentation Using Text and Image Prompts](https://mlsanity.com/paper/2112.10003/) (2021)
- [GLaMM: Pixel Grounding Large Multimodal Model](https://mlsanity.com/paper/2311.03356/) (2023)
- [Validation, comparison, and combination of algorithms for automatic detection of pulmonary nodules in computed tomography images: the LUNA16 challenge](https://mlsanity.com/paper/1612.08012/) (2016)
- [Medical Image Segmentation Using Deep Learning: A Survey](https://mlsanity.com/paper/2009.13120/) (2020)
- [The Importance of Skip Connections in Biomedical Image Segmentation](https://mlsanity.com/paper/1608.04117/) (2016)
- [SAM-Med2D](https://mlsanity.com/paper/2308.16184/) (2023)
- [LViT: Language meets Vision Transformer in Medical Image Segmentation](https://mlsanity.com/paper/2206.14718/) (2022)
- [BiomedParse: a biomedical foundation model for image parsing of everything everywhere all at once](https://mlsanity.com/paper/2405.12971/) (2024)
- [The KiTS21 Challenge: Automatic segmentation of kidneys, renal tumors, and renal cysts in corticomedullary-phase CT](https://mlsanity.com/paper/2307.01984/) (2023)
- [SegVol: Universal and Interactive Volumetric Medical Image Segmentation](https://mlsanity.com/paper/2311.13385/) (2023)
- [NExT-Chat: An LMM for Chat, Detection and Segmentation](https://mlsanity.com/paper/2311.04498/) (2023)
- [PerceptionGPT: Effectively Fusing Visual Perception into LLM](https://mlsanity.com/paper/2311.06612/) (2023)
- [SA-Med2D-20M Dataset: Segment Anything in 2D Medical Imaging with 20 Million masks](https://mlsanity.com/paper/2311.11969/) (2023)
- [LLM-Seg: Bridging Image Segmentation and Large Language Model Reasoning](https://mlsanity.com/paper/2404.08767/) (2024)
- [End-to-end Prostate Cancer Detection in bpMRI via 3D CNNs: Effects of Attention Mechanisms, Clinical Priori and Decoupled False Positive Reduction](https://mlsanity.com/paper/2101.03244/) (2021)
- [Interactive Medical Image Segmentation: A Benchmark Dataset and Baseline](https://mlsanity.com/paper/2411.12814/) (2024)
- [Intracranial Hemorrhage Segmentation Using Deep Convolutional Model](https://mlsanity.com/paper/1910.08643/) (2019)
- [Cross-Modal Conditioned Reconstruction for Language-guided Medical Image Segmentation](https://mlsanity.com/paper/2404.02845/) (2024)
- [Towards a Multimodal Large Language Model with Pixel-Level Insight for Biomedicine](https://mlsanity.com/paper/2412.09278/) (2024)

## Built on by (most cited first, 1 of 1)

- [MedVeriSeg: Teaching LISA-Like Medical Segmentation Models to Verify Query Validity Without Extra Training](https://mlsanity.com/paper/2604.10242/) (2026)

## Abstract (arXiv)

Despite notable progress in text-guided medical image segmentation nowadays, these methods are limited to single-round dialogues and fail to support multi-round reasoning, which is important for medical education scenarios. In this work, we introduce Multi-Round Entity-Level Medical Reasoning Segmentation (MEMR-Seg), a new task that requires generating segmentation masks through multi-round queries with entity-level reasoning, helping learners progressively develop their understanding of medical knowledge. To support this task, we construct MR-MedSeg, a large-scale dataset of 177K multi-round medical segmentation dialogues, featuring entity-based reasoning across rounds. Furthermore, we propose MediRound, an effective baseline model designed for multi-round medical reasoning segmentation. To mitigate the inherent error propagation within the chain-like pipeline of multi-round segmentation, we introduce a lightweight yet effective Judgment & Correction Mechanism during model inference. Experimental results demonstrate that our method effectively addresses the MEMR-Seg task and outperforms conventional medical referring segmentation methods. The project is available at https://github.com/Edisonhimself/MediRound.