# PI-NAIM: Path-Integrated Neural Adaptive Imputation Model

arXiv: https://arxiv.org/abs/2511.11908 · HTML: https://mlsanity.com/paper/2511.11908/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 30 references that are in the map.
- First posted on arXiv 14 Nov 2025.

## Builds on (most cited first, 9 of 9)

- [Simple and Scalable Predictive Uncertainty Estimation using Deep Ensembles](https://mlsanity.com/paper/1612.01474/) (2016)
- [Evidential Deep Learning to Quantify Classification Uncertainty](https://mlsanity.com/paper/1806.01768/) (2018)
- [GAIN: Missing Data Imputation using Generative Adversarial Nets](https://mlsanity.com/paper/1806.02920/) (2018)
- [BRITS: Bidirectional Recurrent Imputation for Time Series](https://mlsanity.com/paper/1805.10572/) (2018)
- [SAITS: Self-Attention-based Imputation for Time Series](https://mlsanity.com/paper/2202.08516/) (2022)
- [Deep Learning for Hyperspectral Image Classification: An Overview](https://mlsanity.com/paper/1910.12861/) (2019)
- [NAOMI: Non-Autoregressive Multiresolution Sequence Imputation](https://mlsanity.com/paper/1901.10946/) (2019)
- [Multimodal Sentiment Analysis using Hierarchical Fusion with Context Modeling](https://mlsanity.com/paper/1806.06228/) (2018)
- [Multiple imputation with missing data indicators](https://mlsanity.com/paper/2103.02033/) (2021)

## Abstract (arXiv)

Medical imaging and multi-modal clinical settings often face the challange of missing modality in their diagnostic pipelines. Existing imputation methods either lack representational capacity or are computationally expensive. We propose PI-NAIM, a novel dual-path architecture that dynamically routes samples to optimized imputation approaches based on missingness complexity. Our framework integrates: (1) intelligent path routing that directs low missingness samples to efficient statistical imputation (MICE) and complex patterns to powerful neural networks (GAIN with temporal analysis); (2) cross-path attention fusion that leverages missingness-aware embeddings to intelligently combine both branches; and (3) end-to-end joint optimization of imputation accuracy and downstream task performance. Extensive experiments on MIMIC-III and multimodal benchmarks demonstrate state-of-the-art performance, achieving RMSE of 0.108 (vs. baselines' 0.119-0.152) and substantial gains in downstream tasks with an AUROC of 0.812 for mortality prediction. PI-NAIM's modular design enables seamless integration into vision pipelines handling incomplete sensor measurements, missing modalities, or corrupted inputs, providing a unified solution for real-world scenario. The code is publicly available at https://github.com/AfifaKhaled/PI-NAIM-Path-Integrated-Neural-Adaptive-Imputation-Model
