# ConSurv: Multimodal Continual Learning for Survival Analysis

arXiv: https://arxiv.org/abs/2511.09853 · HTML: https://mlsanity.com/paper/2511.09853/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Placed in Medical and biomedical MoE, one of 12 directions in Mixture-of-experts.
- Builds on 31 of its 71 references that are in the map.
- First posted on arXiv 13 Nov 2025.

## Placed in

- Mixture-of-experts / [Medical and biomedical MoE](https://mlsanity.com/moe/medical-and-biomedical-moe/)

## Builds on (most cited first, 30 of 31)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Overcoming catastrophic forgetting in neural networks](https://mlsanity.com/paper/1612.00796/) (2016)
- [Outrageously Large Neural Networks: The Sparsely-Gated Mixture-of-Experts Layer](https://mlsanity.com/paper/1701.06538/) (2017)
- [Learning without Forgetting](https://mlsanity.com/paper/1606.09282/) (2016)
- [Gradient Episodic Memory for Continual Learning](https://mlsanity.com/paper/1706.08840/) (2017)
- [Knowledge Distillation: A Survey](https://mlsanity.com/paper/2006.05525/) (2020)
- [Progressive Neural Networks](https://mlsanity.com/paper/1606.04671/) (2016)
- [Attention-based Deep Multiple Instance Learning](https://mlsanity.com/paper/1802.04712/) (2018)
- [Dark Experience for General Continual Learning: a Strong, Simple Baseline](https://mlsanity.com/paper/2004.07211/) (2020)
- [Data Efficient and Weakly Supervised Computational Pathology on Whole Slide Images](https://mlsanity.com/paper/2004.09666/) (2020)
- [Riemannian Walk for Incremental Learning: Understanding Forgetting and Intransigence](https://mlsanity.com/paper/1801.10112/) (2018)
- [Self-Normalizing Neural Networks](https://mlsanity.com/paper/1706.02515/) (2017)
- [TransMIL: Transformer based Correlated Multiple Instance Learning for Whole Slide Image Classification](https://mlsanity.com/paper/2106.00908/) (2021)
- [Class-incremental learning: survey and performance evaluation on image classification](https://mlsanity.com/paper/2010.15277/) (2020)
- [DeepSpeed-MoE: Advancing Mixture-of-Experts Inference and Training to Power Next-Generation AI Scale](https://mlsanity.com/paper/2201.05596/) (2022)
- [Multimodal Learning with Transformers: A Survey](https://mlsanity.com/paper/2206.06488/) (2022)
- [Boosting Continual Learning of Vision-Language Models via Mixture-of-Experts Adapters](https://mlsanity.com/paper/2403.11549/) (2024)
- [A Review of Sparse Expert Models in Deep Learning](https://mlsanity.com/paper/2209.01667/) (2022)
- [Scalable and Order-robust Continual Learning with Additive Parameter Decomposition](https://mlsanity.com/paper/1902.09432/) (2019)
- [Modeling Dense Multimodal Interactions Between Biological Pathways and Histology for Survival Prediction](https://mlsanity.com/paper/2304.06819/) (2023)
- [Multimodal Optimal Transport-based Co-Attention Transformer with Global Structure Consistency for Survival Prediction](https://mlsanity.com/paper/2306.08330/) (2023)
- [CAMEL: A Weakly Supervised Learning Framework for Histopathology Image Segmentation](https://mlsanity.com/paper/1908.10555/) (2019)
- [Cross-Modal Translation and Alignment for Survival Analysis](https://mlsanity.com/paper/2309.12855/) (2023)
- [Federated Continual Learning via Knowledge Fusion: A Survey](https://mlsanity.com/paper/2312.16475/) (2023)
- [Multimodal Prototyping for cancer survival prediction](https://mlsanity.com/paper/2407.00224/) (2024)
- [RATT: Recurrent Attention to Transient Tasks for Continual Image Captioning](https://mlsanity.com/paper/2007.06271/) (2020)
- [ConSlide: Asynchronous Hierarchical Interaction Transformer with Breakup-Reorganize Rehearsal for Continual Whole Slide Image Analysis](https://mlsanity.com/paper/2308.13324/) (2023)
- [Orchestrate Latent Expertise: Advancing Online Continual Learning with Multi-Level Supervision and Reverse Self-Distillation](https://mlsanity.com/paper/2404.00417/) (2024)

## Built on by (most cited first, 2 of 2)

- [TRACE: Trajectory-Aware Comprehensive Evaluation for Deep Research Agents](https://mlsanity.com/paper/2602.21230/) (2026)
- [MergeSurv: Merging-Based Continual Learning for Survival Analysis on Whole-Slide Images](https://mlsanity.com/paper/2607.04747/) (2026)

## Abstract (arXiv)

Survival prediction of cancers is crucial for clinical practice, as it informs mortality risks and influences treatment plans. However, a static model trained on a single dataset fails to adapt to the dynamically evolving clinical environment and continuous data streams, limiting its practical utility. While continual learning (CL) offers a solution to learn dynamically from new datasets, existing CL methods primarily focus on unimodal inputs and suffer from severe catastrophic forgetting in survival prediction. In real-world scenarios, multimodal inputs often provide comprehensive and complementary information, such as whole slide images and genomics; and neglecting inter-modal correlations negatively impacts the performance. To address the two challenges of catastrophic forgetting and complex inter-modal interactions between gigapixel whole slide images and genomics, we propose ConSurv, the first multimodal continual learning (MMCL) method for survival analysis. ConSurv incorporates two key components: Multi-staged Mixture of Experts (MS-MoE) and Feature Constrained Replay (FCR). MS-MoE captures both task-shared and task-specific knowledge at different learning stages of the network, including two modality encoders and the modality fusion component, learning inter-modal relationships. FCR further enhances learned knowledge and mitigates forgetting by restricting feature deviation of previous data at different levels, including encoder-level features of two modalities and the fusion-level representations. Additionally, we introduce a new benchmark integrating four datasets, Multimodal Survival Analysis Incremental Learning (MSAIL), for comprehensive evaluation in the CL setting. Extensive experiments demonstrate that ConSurv outperforms competing methods across multiple metrics.