# Generalizable Blood Cell Detection via Unified Dataset and Faster R-CNN

arXiv: https://arxiv.org/abs/2511.08465 · HTML: https://mlsanity.com/paper/2511.08465/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 6 of its 12 references that are in the map.
- First posted on arXiv 11 Nov 2025.

## Builds on (most cited first, 6 of 6)

- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [Feature Pyramid Networks for Object Detection](https://mlsanity.com/paper/1612.03144/) (2016)
- [Classification of White Blood Cells Using Machine and Deep Learning Models: A Systematic Review](https://mlsanity.com/paper/2308.06296/) (2023)
- [A Curated and Re-annotated Peripheral Blood Cell Dataset Integrating Four Public Resources](https://mlsanity.com/paper/2407.13214/) (2024)

## Abstract (arXiv)

This paper presents a comprehensive methodology and comparative performance analysis for the automated classification and object detection of peripheral blood cells (PBCs) in microscopic images. Addressing the critical challenge of data scarcity and heterogeneity, robust data pipeline was first developed to standardize and merge four public datasets (PBC, BCCD, Chula, Sickle Cell) into a unified resource. Then employed a state-of-the-art Faster R-CNN object detection framework, leveraging a ResNet-50-FPN backbone. Comparative training rigorously evaluated a randomly initialized baseline model (Regimen 1) against a Transfer Learning Regimen (Regimen 2), initialized with weights pre-trained on the Microsoft COCO dataset. The results demonstrate that the Transfer Learning approach achieved significantly faster convergence and superior stability, culminating in a final validation loss of 0.08666, a substantial improvement over the baseline. This validated methodology establishes a robust foundation for building high-accuracy, deployable systems for automated hematological diagnosis.