# SinSEMI: A One-Shot Image Generation Model and Data-Efficient Evaluation Framework for Semiconductor Inspection Equipment

arXiv: https://arxiv.org/abs/2511.06740 · HTML: https://mlsanity.com/paper/2511.06740/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 20 of its 29 references that are in the map.
- First posted on arXiv 10 Nov 2025.

## Builds on (most cited first, 20 of 20)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [Deep Unsupervised Learning using Nonequilibrium Thermodynamics](https://mlsanity.com/paper/1503.03585/) (2015)
- [Generative Adversarial Networks](https://mlsanity.com/paper/2203.00667/) (2022)
- [Training Generative Adversarial Networks with Limited Data](https://mlsanity.com/paper/2006.06676/) (2020)
- [Improving and generalizing flow-based generative models with minibatch optimal transport](https://mlsanity.com/paper/2302.00482/) (2023)
- [SinGAN: Learning a Generative Model from a Single Natural Image](https://mlsanity.com/paper/1905.01164/) (2019)
- [FreeDoM: Training-Free Energy-Guided Conditional Diffusion Model](https://mlsanity.com/paper/2303.09833/) (2023)
- [Diffusion Models for Medical Image Analysis: A Comprehensive Survey](https://mlsanity.com/paper/2211.07804/) (2022)
- [Towards Faster and Stabilized GAN Training for High-fidelity Few-shot Image Synthesis](https://mlsanity.com/paper/2101.04775/) (2021)
- [Freeze the Discriminator: a Simple Baseline for Fine-Tuning GANs](https://mlsanity.com/paper/2002.10964/) (2020)
- [Improved Techniques for Training Single-Image GANs](https://mlsanity.com/paper/2003.11512/) (2020)
- [SinDDM: A Single Image Denoising Diffusion Model](https://mlsanity.com/paper/2211.16582/) (2022)
- [SinFusion: Training Diffusion Models on a Single Image or Video](https://mlsanity.com/paper/2211.11743/) (2022)
- [Drop the GAN: In Defense of Patches Nearest Neighbors as Single Image Generative Models](https://mlsanity.com/paper/2103.15545/) (2021)
- [SinDiffusion: Learning a Diffusion Model from a Single Natural Image](https://mlsanity.com/paper/2211.12445/) (2022)
- [Generating natural images with direct Patch Distributions Matching](https://mlsanity.com/paper/2203.11862/) (2022)
- [Few-shot Image Generation with Diffusion Models](https://mlsanity.com/paper/2211.03264/) (2022)
- [Deep Learning-Based Defect Classification and Detection in SEM Images](https://mlsanity.com/paper/2206.13505/) (2022)
- [Addressing Class Imbalance and Data Limitations in Advanced Node Semiconductor Defect Inspection: A Generative Approach for SEM Images](https://mlsanity.com/paper/2407.10348/) (2024)

## Abstract (arXiv)

In the early stages of semiconductor equipment development, obtaining large quantities of raw optical images poses a significant challenge. This data scarcity hinder the advancement of AI-powered solutions in semiconductor manufacturing. To address this challenge, we introduce SinSEMI, a novel one-shot learning approach that generates diverse and highly realistic images from single optical image. SinSEMI employs a multi-scale flow-based model enhanced with LPIPS (Learned Perceptual Image Patch Similarity) energy guidance during sampling, ensuring both perceptual realism and output variety. We also introduce a comprehensive evaluation framework tailored for this application, which enables a thorough assessment using just two reference images. Through the evaluation against multiple one-shot generation techniques, we demonstrate SinSEMI's superior performance in visual quality, quantitative measures, and downstream tasks. Our experimental results demonstrate that SinSEMI-generated images achieve both high fidelity and meaningful diversity, making them suitable as training data for semiconductor AI applications.
