# Human-AI Co-Embodied Intelligence for Scientific Experimentation and Manufacturing

arXiv: https://arxiv.org/abs/2511.02071 · HTML: https://mlsanity.com/paper/2511.02071/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Multimodal and embodied agents, one of 16 directions in LLM agents and tool use.
- Builds on 13 of its 48 references that are in the map.
- First posted on arXiv 3 Nov 2025.

## Placed in

- LLM agents and tool use / [Multimodal and embodied agents](https://mlsanity.com/agents/multimodal-and-embodied-agents/)

## Builds on (most cited first, 13 of 13)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Shortcut Learning in Deep Neural Networks](https://mlsanity.com/paper/2004.07780/) (2020)
- [The Many Faces of Robustness: A Critical Analysis of Out-of-Distribution Generalization](https://mlsanity.com/paper/2006.16241/) (2020)
- [Competition-Level Code Generation with AlphaCode](https://mlsanity.com/paper/2203.07814/) (2022)
- [CodeXGLUE: A Machine Learning Benchmark Dataset for Code Understanding and Generation](https://mlsanity.com/paper/2102.04664/) (2021)
- [A Survey on Large Language Models for Code Generation](https://mlsanity.com/paper/2406.00515/) (2024)
- [CALVIN: A Benchmark for Language-Conditioned Policy Learning for Long-Horizon Robot Manipulation Tasks](https://mlsanity.com/paper/2112.03227/) (2021)
- [Agent Laboratory: Using LLM Agents as Research Assistants](https://mlsanity.com/paper/2501.04227/) (2025)
- [Self-collaboration Code Generation via ChatGPT](https://mlsanity.com/paper/2304.07590/) (2023)
- [Empowering Biomedical Discovery with AI Agents](https://mlsanity.com/paper/2404.02831/) (2024)
- [ORGANA: A Robotic Assistant for Automated Chemistry Experimentation and Characterization](https://mlsanity.com/paper/2401.06949/) (2024)
- [CRISPR-GPT for Agentic Automation of Gene-editing Experiments](https://mlsanity.com/paper/2404.18021/) (2024)
- [Artificial Intelligence is stupid and causal reasoning won't fix it](https://mlsanity.com/paper/2008.07371/) (2020)

## Abstract (arXiv)

Scientific experimentation and manufacturing rely on prolonged protocol development and complex, multi-step implementation, which require continuous human expertise for precise execution and decision-making, limiting interpretability and scalability. Here, we introduce human-artificial intelligence (AI) co-embodied intelligence, a new form of physical AI that unites human researchers, agentic AI, and wearable hardware. In this paradigm, humans provide precise execution, while agentic AI contributes contextual reasoning, adaptive planning, and analysis. The wearable interface continuously captures experimentation and manufacturing, facilitating seamless communication between humans and AI. We instantiate this paradigm in a microfabrication cleanroom, leading to the agentic-physical experimentation (APEX) system which understands fabrication procedure with accuracy 51% higher than state-of-the-art multimodal large language models/vision language models (LLMs/VLMs), detects and corrects fabrication errors in real-time, and transfers procedural expertise to novice users. Critically, APEX system enables the co-development of fabrication protocols in cleanrooms, overcoming the incompatibility of elastomeric materials in standard microfabrication processes and enabling previously unattainable fabrication outcomes, as demonstrated by the wafer-scale realization of brain-level soft neural probe capable of single-unit-resolution neural recording. These results establish the human-AI co-embodied intelligence that extends agentic reasoning beyond computation into the physical domain, transforming scientific experimentation and manufacturing into autonomous, traceable, interpretable and scalable processes.