# Melanoma Classification Through Deep Ensemble Learning and Explainable AI

arXiv: https://arxiv.org/abs/2511.00246 · HTML: https://mlsanity.com/paper/2511.00246/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 8 of its 27 references that are in the map.
- First posted on arXiv 31 Oct 2025.

## Builds on (most cited first, 8 of 8)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- [Rethinking the Inception Architecture for Computer Vision](https://mlsanity.com/paper/1512.00567/) (2015)
- [Skin Lesion Classification Using Ensembles of Multi-Resolution EfficientNets with Meta Data](https://mlsanity.com/paper/1910.03910/) (2019)
- [Skin Lesion Analysis Towards Melanoma Detection Using Deep Learning Network](https://mlsanity.com/paper/1703.00577/) (2017)
- [Pneumonia Detection on chest X-ray images Using Ensemble of Deep Convolutional Neural Networks](https://mlsanity.com/paper/2312.07965/) (2023)

## Abstract (arXiv)

Melanoma is one of the most aggressive and deadliest skin cancers, leading to mortality if not detected and treated in the early stages. Artificial intelligence techniques have recently been developed to help dermatologists in the early detection of melanoma, and systems based on deep learning (DL) have been able to detect these lesions with high accuracy. However, the entire community must overcome the explainability limit to get the maximum benefit from DL for diagnostics in the healthcare domain. Because of the black box operation's shortcomings in DL models' decisions, there is a lack of reliability and trust in the outcomes. However, Explainable Artificial Intelligence (XAI) can solve this problem by interpreting the predictions of AI systems. This paper proposes a machine learning model using ensemble learning of three state-of-the-art deep transfer Learning networks, along with an approach to ensure the reliability of the predictions by utilizing XAI techniques to explain the basis of the predictions.