# UnifiedFL: A Dynamic Unified Learning Framework for Equitable Federation

arXiv: https://arxiv.org/abs/2510.26350 · HTML: https://mlsanity.com/paper/2510.26350/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 29 of its 42 references that are in the map.
- First posted on arXiv 30 Oct 2025.

## Builds on (most cited first, 29 of 29)

- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Communication-Efficient Learning of Deep Networks from Decentralized Data](https://mlsanity.com/paper/1602.05629/) (2016)
- [Advances and Open Problems in Federated Learning](https://mlsanity.com/paper/1912.04977/) (2019)
- [Federated Optimization in Heterogeneous Networks](https://mlsanity.com/paper/1812.06127/) (2018)
- [MedMNIST v2 -- A large-scale lightweight benchmark for 2D and 3D biomedical image classification](https://mlsanity.com/paper/2110.14795/) (2021)
- [Ensemble Distillation for Robust Model Fusion in Federated Learning](https://mlsanity.com/paper/2006.07242/) (2020)
- [Federated Multi-Task Learning](https://mlsanity.com/paper/1705.10467/) (2017)
- [The Future of Digital Health with Federated Learning](https://mlsanity.com/paper/2003.08119/) (2020)
- [The Medical Segmentation Decathlon](https://mlsanity.com/paper/2106.05735/) (2021)
- [FedBN: Federated Learning on Non-IID Features via Local Batch Normalization](https://mlsanity.com/paper/2102.07623/) (2021)
- [Federated Learning on Non-IID Data Silos: An Experimental Study](https://mlsanity.com/paper/2102.02079/) (2021)
- [Clustered Federated Learning: Model-Agnostic Distributed Multi-Task Optimization under Privacy Constraints](https://mlsanity.com/paper/1910.01991/) (2019)
- [FedMD: Heterogenous Federated Learning via Model Distillation](https://mlsanity.com/paper/1910.03581/) (2019)
- [A large annotated medical image dataset for the development and evaluation of segmentation algorithms](https://mlsanity.com/paper/1902.09063/) (2019)
- [HeteroFL: Computation and Communication Efficient Federated Learning for Heterogeneous Clients](https://mlsanity.com/paper/2010.01264/) (2020)
- [FedDG: Federated Domain Generalization on Medical Image Segmentation via Episodic Learning in Continuous Frequency Space](https://mlsanity.com/paper/2103.06030/) (2021)
- [MedMNIST Classification Decathlon: A Lightweight AutoML Benchmark for Medical Image Analysis](https://mlsanity.com/paper/2010.14925/) (2020)
- [FedKD: Communication Efficient Federated Learning via Knowledge Distillation](https://mlsanity.com/paper/2108.13323/) (2021)
- [Heterogeneous Federated Learning: State-of-the-art and Research Challenges](https://mlsanity.com/paper/2307.10616/) (2023)
- [Cronus: Robust and Heterogeneous Collaborative Learning with Black-Box Knowledge Transfer](https://mlsanity.com/paper/1912.11279/) (2019)
- [Federated Learning for Medical Image Analysis: A Survey](https://mlsanity.com/paper/2306.05980/) (2023)
- [Graph Neural Networks for Learning Equivariant Representations of Neural Networks](https://mlsanity.com/paper/2403.12143/) (2024)
- [FedGroup: Efficient Clustered Federated Learning via Decomposed Data-Driven Measure](https://mlsanity.com/paper/2010.06870/) (2020)
- [pFedLoRA: Model-Heterogeneous Personalized Federated Learning with LoRA Tuning](https://mlsanity.com/paper/2310.13283/) (2023)
- [AutoFL: Enabling Heterogeneity-Aware Energy Efficient Federated Learning](https://mlsanity.com/paper/2107.08147/) (2021)
- [No One Left Behind: Inclusive Federated Learning over Heterogeneous Devices](https://mlsanity.com/paper/2202.08036/) (2022)
- [FIARSE: Model-Heterogeneous Federated Learning via Importance-Aware Submodel Extraction](https://mlsanity.com/paper/2407.19389/) (2024)
- [Categorical Relation-Preserving Contrastive Knowledge Distillation for Medical Image Classification](https://mlsanity.com/paper/2107.03225/) (2021)
- [GNN-based Unified Deep Learning](https://mlsanity.com/paper/2508.10583/) (2025)

## Abstract (arXiv)

Federated learning (FL) has emerged as a key paradigm for collaborative model training across multiple clients without sharing raw data, enabling privacy-preserving applications in areas such as radiology and pathology. However, works on collaborative training across clients with fundamentally different neural architectures and non-identically distributed datasets remain scarce. Existing FL frameworks face several limitations. Despite claiming to support architectural heterogeneity, most recent FL methods only tolerate variants within a single model family (e.g., shallower, deeper, or wider CNNs), still presuming a shared global architecture and failing to accommodate federations where clients deploy fundamentally different network types (e.g., CNNs, GNNs, MLPs). Moreover, existing approaches often address only statistical heterogeneity while overlooking the domain-fracture problem, where each client's data distribution differs markedly from that faced at testing time, undermining model generalizability. When clients use different architectures, have non-identically distributed data, and encounter distinct test domains, current methods perform poorly. To address these challenges, we propose UnifiedFL, a dynamic federated learning framework that represents heterogeneous local networks as nodes and edges in a directed model graph optimized by a shared graph neural network (GNN). UnifiedFL introduces (i) a common GNN to parameterize all architectures, (ii) distance-driven clustering via Euclidean distances between clients' parameters, and (iii) a two-tier aggregation policy balancing convergence and diversity. Experiments on MedMNIST classification and hippocampus segmentation benchmarks demonstrate UnifiedFL's superior performance. Code and data: https://github.com/basiralab/UnifiedFL
