# Standardization of Psychiatric Diagnoses -- Role of Fine-tuned LLM Consortium and OpenAI-gpt-oss Reasoning LLM Enabled Decision Support System

arXiv: https://arxiv.org/abs/2510.25588 · HTML: https://mlsanity.com/paper/2510.25588/

## Key facts

- Cited by 12 papers in the map (data through 14 Oct 2026).
- Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning.
- Builds on 24 of its 53 references that are in the map.
- First posted on arXiv 29 Oct 2025.

## Placed in

- LLM reasoning / [Clinical and biomedical applications](https://mlsanity.com/lr/clinical-and-biomedical-applications/)

## Builds on (most cited first, 24 of 24)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [Qwen2-VL: Enhancing Vision-Language Model's Perception of the World at Any Resolution](https://mlsanity.com/paper/2409.12191/) (2024)
- [QLoRA: Efficient Finetuning of Quantized LLMs](https://mlsanity.com/paper/2305.14314/) (2023)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [LlamaFactory: Unified Efficient Fine-Tuning of 100+ Language Models](https://mlsanity.com/paper/2403.13372/) (2024)
- [gpt-oss-120b & gpt-oss-20b Model Card](https://mlsanity.com/paper/2508.10925/) (2025)
- [Understanding the planning of LLM agents: A survey](https://mlsanity.com/paper/2402.02716/) (2024)
- [Survey on Evaluation of LLM-based Agents](https://mlsanity.com/paper/2503.16416/) (2025)
- [Towards Accurate Differential Diagnosis with Large Language Models](https://mlsanity.com/paper/2312.00164/) (2023)
- [Language Models Enable Simple Systems for Generating Structured Views of Heterogeneous Data Lakes](https://mlsanity.com/paper/2304.09433/) (2023)
- [Data-efficient Fine-tuning for LLM-based Recommendation](https://mlsanity.com/paper/2401.17197/) (2024)
- [LLM as a Mastermind: A Survey of Strategic Reasoning with Large Language Models](https://mlsanity.com/paper/2404.01230/) (2024)
- [Wider and Deeper LLM Networks are Fairer LLM Evaluators](https://mlsanity.com/paper/2308.01862/) (2023)
- [LLM Unlearning via Loss Adjustment with Only Forget Data](https://mlsanity.com/paper/2410.11143/) (2024)
- [A Tutorial on LLM Reasoning: Relevant Methods behind ChatGPT o1](https://mlsanity.com/paper/2502.10867/) (2025)
- [DrHouse: An LLM-empowered Diagnostic Reasoning System through Harnessing Outcomes from Sensor Data and Expert Knowledge](https://mlsanity.com/paper/2405.12541/) (2024)
- [MDD-5k: A New Diagnostic Conversation Dataset for Mental Disorders Synthesized via Neuro-Symbolic LLM Agents](https://mlsanity.com/paper/2408.12142/) (2024)
- [Proof-of-TBI -- Fine-Tuned Vision Language Model Consortium and OpenAI-o3 Reasoning LLM-Based Medical Diagnosis Support System for Mild Traumatic Brain Injury (TBI) Prediction](https://mlsanity.com/paper/2504.18671/) (2025)
- [LoHan: Low-Cost High-Performance Framework to Fine-Tune 100B Model on a Consumer GPU](https://mlsanity.com/paper/2403.06504/) (2024)
- [VTutor: An Open-Source SDK for Generative AI-Powered Animated Pedagogical Agents with Multi-Media Output](https://mlsanity.com/paper/2502.04103/) (2025)
- [Large Language Models for Interpretable Mental Health Diagnosis](https://mlsanity.com/paper/2501.07653/) (2025)
- [On-Device Qwen2.5: Efficient LLM Inference with Model Compression and Hardware Acceleration](https://mlsanity.com/paper/2504.17376/) (2025)
- [Advancements in Machine Learning and Deep Learning for Early Detection and Management of Mental Health Disorder](https://mlsanity.com/paper/2412.06147/) (2024)

## Built on by (most cited first, 12 of 12)

- [A Practical Guide for Designing, Developing, and Deploying Production-Grade Agentic AI Workflows](https://mlsanity.com/paper/2512.08769/) (2025)
- [Towards Responsible and Explainable AI Agents with Consensus-Driven Reasoning](https://mlsanity.com/paper/2512.21699/) (2025)
- [ASTRIDE: A Security Threat Modeling Platform for Agentic-AI Applications](https://mlsanity.com/paper/2512.04785/) (2025)
- [A Practical Guide to Agentic AI Transition in Organizations](https://mlsanity.com/paper/2602.10122/) (2026)
- [AI Trust OS -- A Continuous Governance Framework for Autonomous AI Observability and Zero-Trust Compliance in Enterprise Environments](https://mlsanity.com/paper/2604.04749/) (2026)
- [Flowr -- Scaling Up Retail Supply Chain Operations Through Agentic AI in Large Scale Supermarket Chains](https://mlsanity.com/paper/2604.05987/) (2026)
- [Toward Zero-Egress Psychiatric AI: On-Device LLM Deployment for Privacy-Preserving Mental Health Decision Support](https://mlsanity.com/paper/2604.18302/) (2026)
- [Think Before You Act -- A Neurocognitive Governance Model for Autonomous AI Agents](https://mlsanity.com/paper/2604.25684/) (2026)
- [MindGap: A Conversational AI Framework for Upstream Neuroplastic Intervention in Post-Traumatic Stress Disorder](https://mlsanity.com/paper/2605.14660/) (2026)
- [Train the Trainers -- An Agentic AI Framework for Peer-Based Mental Health Support in Battlefield Environments](https://mlsanity.com/paper/2605.16269/) (2026)
- [Human-AI Agent Interaction as a Neuroplastic Training Environment](https://mlsanity.com/paper/2607.12823/) (2026)
- [OpenClaw and Ollama in Agentic AI: Toward Fully Autonomous and Scalable AI Agent Systems](https://mlsanity.com/paper/2607.28629/) (2026)

## Abstract (arXiv)

The diagnosis of most mental disorders, including psychiatric evaluations, primarily depends on dialogues between psychiatrists and patients. This subjective process can lead to variability in diagnoses across clinicians and patients, resulting in inconsistencies and challenges in achieving reliable outcomes. To address these issues and standardize psychiatric diagnoses, we propose a Fine-Tuned Large Language Model (LLM) Consortium and OpenAI-gpt-oss Reasoning LLM-enabled Decision Support System for the clinical diagnosis of mental disorders. Our approach leverages fine-tuned LLMs trained on conversational datasets involving psychiatrist-patient interactions focused on mental health conditions (e.g., depression). The diagnostic predictions from individual models are aggregated through a consensus-based decision-making process, refined by the OpenAI-gpt-oss reasoning LLM. We propose a novel method for deploying LLM agents that orchestrate communication between the LLM consortium and the reasoning LLM, ensuring transparency, reliability, and responsible AI across the entire diagnostic workflow. Experimental results demonstrate the transformative potential of combining fine-tuned LLMs with a reasoning model to create a robust and highly accurate diagnostic system for mental health assessment. A prototype of the proposed platform, integrating three fine-tuned LLMs with the OpenAI-gpt-oss reasoning LLM, was developed in collaboration with the U.S. Army Medical Research Team in Norfolk, Virginia, USA. To the best of our knowledge, this work represents the first application of a fine-tuned LLM consortium integrated with a reasoning LLM for clinical mental health diagnosis paving the way for next-generation AI-powered eHealth systems aimed at standardizing psychiatric diagnoses.