# ReplicationBench: Can AI Agents Replicate Astrophysics Research Papers?

arXiv: https://arxiv.org/abs/2510.24591 · HTML: https://mlsanity.com/paper/2510.24591/

## Key facts

- Cited by 11 papers in the map (data through 14 Oct 2026).
- Placed in Web, search, and research agents, one of 16 directions in LLM agents and tool use.
- Builds on 21 of its 70 references that are in the map.
- First posted on arXiv 28 Oct 2025.

## Placed in

- LLM agents and tool use / [Web, search, and research agents](https://mlsanity.com/agents/web-search-and-research-agents/)

## Builds on (most cited first, 21 of 21)

- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [SWE-bench: Can Language Models Resolve Real-World GitHub Issues?](https://mlsanity.com/paper/2310.06770/) (2023)
- [GPQA: A Graduate-Level Google-Proof Q&A Benchmark](https://mlsanity.com/paper/2311.12022/) (2023)
- [τ-bench: A Benchmark for Tool-Agent-User Interaction in Real-World Domains](https://mlsanity.com/paper/2406.12045/) (2024)
- [The AI Scientist: Towards Fully Automated Open-Ended Scientific Discovery](https://mlsanity.com/paper/2408.06292/) (2024)
- [The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Search](https://mlsanity.com/paper/2504.08066/) (2025)
- [PlanBench: An Extensible Benchmark for Evaluating Large Language Models on Planning and Reasoning about Change](https://mlsanity.com/paper/2206.10498/) (2022)
- [MLAgentBench: Evaluating Language Agents on Machine Learning Experimentation](https://mlsanity.com/paper/2310.03302/) (2023)
- [PaperBench: Evaluating AI's Ability to Replicate AI Research](https://mlsanity.com/paper/2504.01848/) (2025)
- [ResearchAgent: Iterative Research Idea Generation over Scientific Literature with Large Language Models](https://mlsanity.com/paper/2404.07738/) (2024)
- [RE-Bench: Evaluating frontier AI R&D capabilities of language model agents against human experts](https://mlsanity.com/paper/2411.15114/) (2024)
- [LAB-Bench: Measuring Capabilities of Language Models for Biology Research](https://mlsanity.com/paper/2407.10362/) (2024)
- [Measuring AI Ability to Complete Long Software Tasks](https://mlsanity.com/paper/2503.14499/) (2025)
- [CORE-Bench: Fostering the Credibility of Published Research Through a Computational Reproducibility Agent Benchmark](https://mlsanity.com/paper/2409.11363/) (2024)
- [BixBench: a Comprehensive Benchmark for LLM-based Agents in Computational Biology](https://mlsanity.com/paper/2503.00096/) (2025)
- [Many Heads Are Better Than One: Improved Scientific Idea Generation by A LLM-Based Multi-Agent System](https://mlsanity.com/paper/2410.09403/) (2024)
- [Gravity-Bench-v1: A Benchmark on Gravitational Physics Discovery for Agents](https://mlsanity.com/paper/2501.18411/) (2025)
- [AstroM3: A self-supervised multimodal model for astronomy](https://mlsanity.com/paper/2411.08842/) (2024)
- [AstroAgents: A Multi-Agent AI for Hypothesis Generation from Mass Spectrometry Data](https://mlsanity.com/paper/2503.23170/) (2025)
- [pathfinder: A Semantic Framework for Literature Review and Knowledge Discovery in Astronomy](https://mlsanity.com/paper/2408.01556/) (2024)
- [Representation Learning for Time-Domain High-Energy Astrophysics: Discovery of Extragalactic Fast X-ray Transient XRT 200515](https://mlsanity.com/paper/2412.01150/) (2024)

## Built on by (most cited first, 11 of 11)

- [SkillsBench: Benchmarking How Well Agent Skills Work Across Diverse Tasks](https://mlsanity.com/paper/2602.12670/) (2026)
- [Building Effective AI Coding Agents for the Terminal: Scaffolding, Harness, Context Engineering, and Lessons Learned](https://mlsanity.com/paper/2603.05344/) (2026)
- [Memory Transfer Learning: How Memories are Transferred Across Domains in Coding Agents](https://mlsanity.com/paper/2604.14004/) (2026)
- [Pitfalls in Evaluating Interpretability Agents](https://mlsanity.com/paper/2603.20101/) (2026)
- [Towards Autonomous and Auditable Medical Imaging Model Development](https://mlsanity.com/paper/2607.10522/) (2026)
- [ARA: Agentic Reproducibility Assessment For Scalable Support Of Scientific Peer-Review](https://mlsanity.com/paper/2605.02651/) (2026)
- [BilliardPhys-Bench: Benchmarking Physical Reasoning and Visual Dynamics of Multimodal LLMs](https://mlsanity.com/paper/2605.30900/) (2026)
- [Reasoning4Sciences: Bridging Reasoning Language Models to All Scientific Branches](https://mlsanity.com/paper/2606.01145/) (2026)
- [RECLAIM: Can Agents Reproduce the Claims of Machine Learning Papers?](https://mlsanity.com/paper/2609.28850/) (2026)
- [CompMat-Bench: Benchmarking AI Agents for Computational Materials Science](https://mlsanity.com/paper/2610.00636/) (2026)
- [BioStudyBench: Evaluating Agents on Post-Cutoff Biomedical Studies](https://mlsanity.com/paper/2610.07614/) (2026)

## Abstract (arXiv)

Frontier AI agents show increasing promise as scientific research assistants, and may eventually be useful for extended, open-ended research workflows. However, in order to use agents for novel research, we must first assess the underlying faithfulness and correctness of their work. To evaluate agents as research assistants, we introduce ReplicationBench, an evaluation framework that tests whether agents can replicate entire research papers drawn from the astrophysics literature. Astrophysics, where research relies heavily on archival data and computational study while requiring little real-world experimentation, is a particularly useful testbed for AI agents in scientific research. We split each paper into tasks which require agents to replicate the paper's core contributions, including the experimental setup, derivations, data analysis, and codebase. Each task is co-developed with the original paper authors and targets a key scientific result, enabling objective evaluation of both faithfulness (adherence to original methods) and correctness (technical accuracy of results). ReplicationBench is extremely challenging for current frontier language models: even the best-performing language models score under 20%. We analyze ReplicationBench trajectories in collaboration with domain experts and find a rich, diverse set of failure modes for agents in scientific research. ReplicationBench establishes the first benchmark of paper-scale, expert-validated astrophysics research tasks, reveals insights about agent performance generalizable to other domains of data-driven science, and provides a scalable framework for measuring AI agents' reliability in scientific research.
