# Towards the Automatic Segmentation, Modeling and Meshing of the Aortic Vessel Tree from Multicenter Acquisitions: An Overview of the SEG.A. 2023 Segmentation of the Aorta Challenge

arXiv: https://arxiv.org/abs/2510.24009 · HTML: https://mlsanity.com/paper/2510.24009/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 16 of its 39 references that are in the map.
- First posted on arXiv 28 Oct 2025.

## Builds on (most cited first, 16 of 16)

- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [CBAM: Convolutional Block Attention Module](https://mlsanity.com/paper/1807.06521/) (2018)
- [3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation](https://mlsanity.com/paper/1606.06650/) (2016)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [The Medical Segmentation Decathlon](https://mlsanity.com/paper/2106.05735/) (2021)
- [MONAI: An open-source framework for deep learning in healthcare](https://mlsanity.com/paper/2211.02701/) (2022)
- [Road Extraction by Deep Residual U-Net](https://mlsanity.com/paper/1711.10684/) (2017)
- [3D MRI brain tumor segmentation using autoencoder regularization](https://mlsanity.com/paper/1810.11654/) (2018)
- [The KiTS19 Challenge Data: 300 Kidney Tumor Cases with Clinical Context, CT Semantic Segmentations, and Surgical Outcomes](https://mlsanity.com/paper/1904.00445/) (2019)
- [A Topological Loss Function for Deep-Learning based Image Segmentation using Persistent Homology](https://mlsanity.com/paper/1910.01877/) (2019)
- [Reducing the Hausdorff Distance in Medical Image Segmentation with Convolutional Neural Networks](https://mlsanity.com/paper/1904.10030/) (2019)
- [Towards a Guideline for Evaluation Metrics in Medical Image Segmentation](https://mlsanity.com/paper/2202.05273/) (2022)
- [BIAS: Transparent reporting of biomedical image analysis challenges](https://mlsanity.com/paper/1910.04071/) (2019)
- [Aorta Segmentation from 3D CT in MICCAI SEG.A. 2023 Challenge](https://mlsanity.com/paper/2310.04114/) (2023)
- [Automatic Aorta Segmentation with Heavily Augmented, High-Resolution 3-D ResUNet: Contribution to the SEG.A Challenge](https://mlsanity.com/paper/2310.15827/) (2023)
- [Automated cross-sectional view selection in CT angiography of aortic dissections with uncertainty awareness and retrospective clinical annotations](https://mlsanity.com/paper/2111.11269/) (2021)

## Built on by (most cited first, 2 of 2)

- [ReX-MLE: The Autonomous Agent Benchmark for Medical Imaging Challenges](https://mlsanity.com/paper/2512.17838/) (2025)
- [Towards Autonomous and Auditable Medical Imaging Model Development](https://mlsanity.com/paper/2607.10522/) (2026)

## Abstract (arXiv)

The automated analysis of the aortic vessel tree (AVT) from computed tomography angiography (CTA) holds immense clinical potential, but its development has been impeded by a lack of shared, high-quality data. We launched the SEG.A. challenge to catalyze progress in this field by introducing a large, publicly available, multi-institutional dataset for AVT segmentation. The challenge benchmarked automated algorithms on a hidden test set, with subsequent optional tasks in surface meshing for computational simulations. Our findings reveal a clear convergence on deep learning methodologies, with 3D U-Net architectures dominating the top submissions. A key result was that an ensemble of the highest-ranking algorithms significantly outperformed individual models, highlighting the benefits of model fusion. Performance was strongly linked to algorithmic design, particularly the use of customized post-processing steps, and the characteristics of the training data. This initiative not only establishes a new performance benchmark but also provides a lasting resource to drive future innovation toward robust, clinically translatable tools.
