# A Survey of AI Scientists

arXiv: https://arxiv.org/abs/2510.23045 · HTML: https://mlsanity.com/paper/2510.23045/

## Key facts

- Cited by 11 papers in the map (data through 14 Oct 2026).
- Builds on 72 of its 115 references that are in the map.
- First posted on arXiv 27 Oct 2025.

## Builds on (most cited first, 30 of 72)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [ChartQA: A Benchmark for Question Answering about Charts with Visual and Logical Reasoning](https://mlsanity.com/paper/2203.10244/) (2022)
- [The AI Scientist: Towards Fully Automated Open-Ended Scientific Discovery](https://mlsanity.com/paper/2408.06292/) (2024)
- [AI Feynman: a Physics-Inspired Method for Symbolic Regression](https://mlsanity.com/paper/1905.11481/) (2019)
- [DS-1000: A Natural and Reliable Benchmark for Data Science Code Generation](https://mlsanity.com/paper/2211.11501/) (2022)
- [The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Search](https://mlsanity.com/paper/2504.08066/) (2025)
- [Accelerating scientific discovery with Co-Scientist](https://mlsanity.com/paper/2502.18864/) (2025)
- [MLAgentBench: Evaluating Language Agents on Machine Learning Experimentation](https://mlsanity.com/paper/2310.03302/) (2023)
- [DeepResearcher: Scaling Deep Research via Reinforcement Learning in Real-world Environments](https://mlsanity.com/paper/2504.03160/) (2025)
- [CharXiv: Charting Gaps in Realistic Chart Understanding in Multimodal LLMs](https://mlsanity.com/paper/2406.18521/) (2024)
- [Chain-of-Table: Evolving Tables in the Reasoning Chain for Table Understanding](https://mlsanity.com/paper/2401.04398/) (2024)
- [PaperQA: Retrieval-Augmented Generative Agent for Scientific Research](https://mlsanity.com/paper/2312.07559/) (2023)
- [InfiAgent-DABench: Evaluating Agents on Data Analysis Tasks](https://mlsanity.com/paper/2401.05507/) (2024)
- [Language agents achieve superhuman synthesis of scientific knowledge](https://mlsanity.com/paper/2409.13740/) (2024)
- [ChartX & ChartVLM: A Versatile Benchmark and Foundation Model for Complicated Chart Reasoning](https://mlsanity.com/paper/2402.12185/) (2024)
- [TableBench: A Comprehensive and Complex Benchmark for Table Question Answering](https://mlsanity.com/paper/2408.09174/) (2024)
- [DS-Agent: Automated Data Science by Empowering Large Language Models with Case-Based Reasoning](https://mlsanity.com/paper/2402.17453/) (2024)
- [DSBench: How Far Are Data Science Agents from Becoming Data Science Experts?](https://mlsanity.com/paper/2409.07703/) (2024)
- [DiscoveryBench: Towards Data-Driven Discovery with Large Language Models](https://mlsanity.com/paper/2407.01725/) (2024)
- [WritingBench: A Comprehensive Benchmark for Generative Writing](https://mlsanity.com/paper/2503.05244/) (2025)
- [Large Language Models for Automated Open-domain Scientific Hypotheses Discovery](https://mlsanity.com/paper/2309.02726/) (2023)
- [AI-Researcher: Autonomous Scientific Innovation](https://mlsanity.com/paper/2505.18705/) (2025)
- [SciAgents: Automating scientific discovery through multi-agent intelligent graph reasoning](https://mlsanity.com/paper/2409.05556/) (2024)
- [Natural Language to Code Generation in Interactive Data Science Notebooks](https://mlsanity.com/paper/2212.09248/) (2022)
- [LLM4SR: A Survey on Large Language Models for Scientific Research](https://mlsanity.com/paper/2501.04306/) (2025)
- [AutomaTikZ: Text-Guided Synthesis of Scientific Vector Graphics with TikZ](https://mlsanity.com/paper/2310.00367/) (2023)
- [Delving into LLM-assisted writing in biomedical publications through excess vocabulary](https://mlsanity.com/paper/2406.07016/) (2024)
- [BLADE: Benchmarking Language Model Agents for Data-Driven Science](https://mlsanity.com/paper/2408.09667/) (2024)
- [From AI for Science to Agentic Science: A Survey on Autonomous Scientific Discovery](https://mlsanity.com/paper/2508.14111/) (2025)
- [MOOSE-Chem: Large Language Models for Rediscovering Unseen Chemistry Scientific Hypotheses](https://mlsanity.com/paper/2410.07076/) (2024)

## Built on by (most cited first, 11 of 11)

- [PostTrainBench: Can LLM Agents Automate LLM Post-Training?](https://mlsanity.com/paper/2603.08640/) (2026)
- [Toward Generalist Autonomous Research via Hypothesis-Tree Refinement](https://mlsanity.com/paper/2606.11926/) (2026)
- [Omni-SimpleMem: Autoresearch-Guided Discovery of Lifelong Multimodal Agent Memory](https://mlsanity.com/paper/2604.01007/) (2026)
- [AI for Auto-Research: Roadmap & User Guide](https://mlsanity.com/paper/2605.18661/) (2026)
- [AutoResearch AI: Towards AI-Powered Research Automation for Scientific Discovery](https://mlsanity.com/paper/2605.23204/) (2026)
- [Autonomous Research Agents: A Survey of AI Scientists and the Verification Gap](https://mlsanity.com/paper/2608.05179/) (2026)
- [DeepInflation: an AI agent for research and model discovery of inflation](https://mlsanity.com/paper/2601.14288/) (2026)
- [SciAtlas: A Computable Atlas of Science for Knowledge-Grounded AI Research](https://mlsanity.com/paper/2605.22878/) (2026)
- [RankLLM: Weighted Ranking of LLMs by Quantifying Question Difficulty](https://mlsanity.com/paper/2602.12424/) (2026)
- [An LLM System for Autonomous Variational Quantum Circuit Design](https://mlsanity.com/paper/2606.13380/) (2026)
- [Toward Auto-Research: Mining Falsifiable Research Ideas from Paper Knowledge Graphs with Categorical Structure](https://mlsanity.com/paper/2608.20361/) (2026)

## Abstract (arXiv)

Artificial intelligence is undergoing a profound transition from a computational instrument to an autonomous originator of scientific knowledge. This emerging paradigm, the AI scientist, is architected to emulate the complete scientific workflow-from initial hypothesis generation to the final synthesis of publishable findings-thereby promising to fundamentally reshape the pace and scale of discovery. However, the rapid and unstructured proliferation of these systems has created a fragmented research landscape, obscuring overarching methodological principles and developmental trends. This survey provides a systematic and comprehensive synthesis of this domain by introducing a unified, six-stage methodological framework that deconstructs the end-to-end scientific process into: Literature Review, Idea Generation, Experimental Preparation, Experimental Execution, Scientific Writing, and Paper Generation. Through this analytical lens, we chart the field's evolution from early Foundational Modules (2022-2023) to integrated Closed-Loop Systems (2024), and finally to the current frontier of Scalability, Impact, and Human-AI Collaboration (2025-present). By rigorously synthesizing these developments, this survey not only clarifies the current state of autonomous science but also provides a critical roadmap for overcoming remaining challenges in robustness and governance, ultimately guiding the next generation of systems toward becoming trustworthy and indispensable partners in human scientific inquiry.