# BrainMCLIP: Brain Image Decoding with Multi-Layer feature Fusion of CLIP

arXiv: https://arxiv.org/abs/2510.19332 · HTML: https://mlsanity.com/paper/2510.19332/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 16 of its 32 references that are in the map.
- First posted on arXiv 22 Oct 2025.

## Builds on (most cited first, 16 of 16)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Generative Adversarial Networks](https://mlsanity.com/paper/2203.00667/) (2022)
- [Rethinking the Inception Architecture for Computer Vision](https://mlsanity.com/paper/1512.00567/) (2015)
- [Unsupervised Learning of Visual Features by Contrasting Cluster Assignments](https://mlsanity.com/paper/2006.09882/) (2020)
- [Reconstructing the Mind's Eye: fMRI-to-Image with Contrastive Learning and Diffusion Priors](https://mlsanity.com/paper/2305.18274/) (2023)
- [Generic decoding of seen and imagined objects using hierarchical visual features](https://mlsanity.com/paper/1510.06479/) (2015)
- [ClearCLIP: Decomposing CLIP Representations for Dense Vision-Language Inference](https://mlsanity.com/paper/2407.12442/) (2024)
- [MindEye2: Shared-Subject Models Enable fMRI-To-Image With 1 Hour of Data](https://mlsanity.com/paper/2403.11207/) (2024)
- [Natural scene reconstruction from fMRI signals using generative latent diffusion](https://mlsanity.com/paper/2303.05334/) (2023)
- [Mind Reader: Reconstructing complex images from brain activities](https://mlsanity.com/paper/2210.01769/) (2022)
- [MindBridge: A Cross-Subject Brain Decoding Framework](https://mlsanity.com/paper/2404.07850/) (2024)
- [MindDiffuser: Controlled Image Reconstruction from Human Brain Activity with Semantic and Structural Diffusion](https://mlsanity.com/paper/2308.04249/) (2023)
- [APPLeNet: Visual Attention Parameterized Prompt Learning for Few-Shot Remote Sensing Image Generalization using CLIP](https://mlsanity.com/paper/2304.05995/) (2023)
- [CLIPer: Hierarchically Improving Spatial Representation of CLIP for Open-Vocabulary Semantic Segmentation](https://mlsanity.com/paper/2411.13836/) (2024)

## Built on by (most cited first, 1 of 1)

- [FPED: A Functional-Network Prior-Guided Mixture-of-Experts Framework for Interpretable Brain Decoding](https://mlsanity.com/paper/2605.19279/) (2026)

## Abstract (arXiv)

Decoding images from fMRI often involves mapping brain activity to CLIP's final semantic layer. To capture finer visual details, many approaches add a parameter-intensive VAE-based pipeline. However, these approaches overlook rich object information within CLIP's intermediate layers and contradicts the brain's functionally hierarchical. We introduce BrainMCLIP, which pioneers a parameter-efficient, multi-layer fusion approach guided by human visual system's functional hierarchy, eliminating the need for such a separate VAE pathway. BrainMCLIP aligns fMRI signals from functionally distinct visual areas (low-/high-level) to corresponding intermediate and final CLIP layers, respecting functional hierarchy. We further introduce a Cross-Reconstruction strategy and a novel multi-granularity loss. Results show BrainMCLIP achieves highly competitive performance, particularly excelling on high-level semantic metrics where it matches or surpasses SOTA(state-of-the-art) methods, including those using VAE pipelines. Crucially, it achieves this with substantially fewer parameters, demonstrating a reduction of 71.7%(Table.reftab:compareclipvae) compared to top VAE-based SOTA methods, by avoiding the VAE pathway. By leveraging intermediate CLIP features, it effectively captures visual details often missed by CLIP-only approaches, striking a compelling balance between semantic accuracy and detail fidelity without requiring a separate VAE pipeline.