# GOOD: Training-Free Guided Diffusion Sampling for Out-of-Distribution Detection

arXiv: https://arxiv.org/abs/2510.17131 · HTML: https://mlsanity.com/paper/2510.17131/

## Key facts

- Cited by 5 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 55 of its 70 references that are in the map.
- First posted on arXiv 20 Oct 2025.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 30 of 55)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [Classifier-Free Diffusion Guidance](https://mlsanity.com/paper/2207.12598/) (2022)
- [Generative Modeling by Estimating Gradients of the Data Distribution](https://mlsanity.com/paper/1907.05600/) (2019)
- [A Baseline for Detecting Misclassified and Out-of-Distribution Examples in Neural Networks](https://mlsanity.com/paper/1610.02136/) (2016)
- [Describing Textures in the Wild](https://mlsanity.com/paper/1311.3618/) (2013)
- [A Simple Unified Framework for Detecting Out-of-Distribution Samples and Adversarial Attacks](https://mlsanity.com/paper/1807.03888/) (2018)
- [LSUN: Construction of a Large-scale Image Dataset using Deep Learning with Humans in the Loop](https://mlsanity.com/paper/1506.03365/) (2015)
- [Enhancing The Reliability of Out-of-distribution Image Detection in Neural Networks](https://mlsanity.com/paper/1706.02690/) (2017)
- [Energy-based Out-of-distribution Detection](https://mlsanity.com/paper/2010.03759/) (2020)
- [Deep Anomaly Detection with Outlier Exposure](https://mlsanity.com/paper/1812.04606/) (2018)
- [Generalized Out-of-Distribution Detection: A Survey](https://mlsanity.com/paper/2110.11334/) (2021)
- [Deep Neural Networks are Easily Fooled: High Confidence Predictions for Unrecognizable Images](https://mlsanity.com/paper/1412.1897/) (2014)
- [Out-of-Distribution Detection with Deep Nearest Neighbors](https://mlsanity.com/paper/2204.06507/) (2022)
- [ReAct: Out-of-distribution Detection With Rectified Activations](https://mlsanity.com/paper/2111.12797/) (2021)
- [Scaling Out-of-Distribution Detection for Real-World Settings](https://mlsanity.com/paper/1911.11132/) (2019)
- [Universal Guidance for Diffusion Models](https://mlsanity.com/paper/2302.07121/) (2023)
- [Generalized ODIN: Detecting Out-of-distribution Image without Learning from Out-of-distribution Data](https://mlsanity.com/paper/2002.11297/) (2020)
- [Your Classifier is Secretly an Energy Based Model and You Should Treat it Like One](https://mlsanity.com/paper/1912.03263/) (2019)
- [ViM: Out-Of-Distribution with Virtual-logit Matching](https://mlsanity.com/paper/2203.10807/) (2022)
- [Training Confidence-calibrated Classifiers for Detecting Out-of-Distribution Samples](https://mlsanity.com/paper/1711.09325/) (2017)
- [On the Importance of Gradients for Detecting Distributional Shifts in the Wild](https://mlsanity.com/paper/2110.00218/) (2021)
- [Score-based diffusion models for accelerated MRI](https://mlsanity.com/paper/2110.05243/) (2021)
- [VOS: Learning What You Don't Know by Virtual Outlier Synthesis](https://mlsanity.com/paper/2202.01197/) (2022)
- [FreeDoM: Training-Free Energy-Guided Conditional Diffusion Model](https://mlsanity.com/paper/2303.09833/) (2023)
- [Learning Confidence for Out-of-Distribution Detection in Neural Networks](https://mlsanity.com/paper/1802.04865/) (2018)

## Built on by (most cited first, 5 of 5)

- [ManifoldGD: Training-Free Hierarchical Manifold Guidance for Diffusion-Based Dataset Distillation](https://mlsanity.com/paper/2602.23295/) (2026)
- [MacTok: Robust Continuous Tokenization for Image Generation](https://mlsanity.com/paper/2603.29634/) (2026)
- [Reasoning on the Manifold: Bidirectional Consistency for Self-Verification in Diffusion Language Models](https://mlsanity.com/paper/2604.16565/) (2026)
- [DINO-VO: Learning Where to Focus for Enhanced State Estimation](https://mlsanity.com/paper/2604.04055/) (2026)
- [Beyond Empirical Support: Structured Outlier Generation via Sinkhorn Optimal Transport](https://mlsanity.com/paper/2609.31470/) (2026)

## Abstract (arXiv)

Recent advancements have explored text-to-image diffusion models for synthesizing out-of-distribution (OOD) samples, substantially enhancing the performance of OOD detection. However, existing approaches typically rely on perturbing text-conditioned embeddings, resulting in semantic instability and insufficient shift diversity, which limit generalization to realistic OOD. To address these challenges, we propose GOOD, a novel and flexible framework that directly guides diffusion sampling trajectories towards OOD regions using off-the-shelf in-distribution (ID) classifiers. GOOD incorporates dual-level guidance: (1) Image-level guidance based on the gradient of log partition to reduce input likelihood, drives samples toward low-density regions in pixel space. (2) Feature-level guidance, derived from k-NN distance in the classifier's latent space, promotes sampling in feature-sparse regions. Hence, this dual-guidance design enables more controllable and diverse OOD sample generation. Additionally, we introduce a unified OOD score that adaptively combines image and feature discrepancies, enhancing detection robustness. We perform thorough quantitative and qualitative analyses to evaluate the effectiveness of GOOD, demonstrating that training with samples generated by GOOD can notably enhance OOD detection performance.