# Multimodal Retrieval-Augmented Generation with Large Language Models for Medical VQA

arXiv: https://arxiv.org/abs/2510.13856 · HTML: https://mlsanity.com/paper/2510.13856/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Placed in Medical and biomedical RAG, one of 15 directions in Retrieval-augmented generation.
- Builds on 20 of its 39 references that are in the map.
- First posted on arXiv 12 Oct 2025.

## Placed in

- Retrieval-augmented generation / [Medical and biomedical RAG](https://mlsanity.com/rag/medical-and-biomedical-rag/)

## Builds on (most cited first, 20 of 20)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [VQA: Visual Question Answering](https://mlsanity.com/paper/1505.00468/) (2015)
- [ViLBERT: Pretraining Task-Agnostic Visiolinguistic Representations for Vision-and-Language Tasks](https://mlsanity.com/paper/1908.02265/) (2019)
- [DeBERTa: Decoding-enhanced BERT with Disentangled Attention](https://mlsanity.com/paper/2006.03654/) (2020)
- [LXMERT: Learning Cross-Modality Encoder Representations from Transformers](https://mlsanity.com/paper/1908.07490/) (2019)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [MedCLIP: Contrastive Learning from Unpaired Medical Images and Text](https://mlsanity.com/paper/2210.10163/) (2022)
- [PathVQA: 30000+ Questions for Medical Visual Question Answering](https://mlsanity.com/paper/2003.10286/) (2020)
- [SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answering](https://mlsanity.com/paper/2102.09542/) (2021)
- [Deep Modular Co-Attention Networks for Visual Question Answering](https://mlsanity.com/paper/1906.10770/) (2019)
- [Benchmarking Retrieval-Augmented Generation for Medicine](https://mlsanity.com/paper/2402.13178/) (2024)
- [Medical Visual Question Answering: A Survey](https://mlsanity.com/paper/2111.10056/) (2021)
- [MMBERT: Multimodal BERT Pretraining for Improved Medical VQA](https://mlsanity.com/paper/2104.01394/) (2021)
- [Ask Your Neurons: A Neural-based Approach to Answering Questions about Images](https://mlsanity.com/paper/1505.01121/) (2015)
- [MedFrameQA: A Multi-Image Medical VQA Benchmark for Clinical Reasoning](https://mlsanity.com/paper/2505.16964/) (2025)
- [RAMM: Retrieval-augmented Biomedical Visual Question Answering with Multi-modal Pre-training](https://mlsanity.com/paper/2303.00534/) (2023)
- [deltaBLEU: A Discriminative Metric for Generation Tasks with Intrinsically Diverse Targets](https://mlsanity.com/paper/1506.06863/) (2015)
- [R-LLaVA: Improving Med-VQA Understanding through Visual Region of Interest](https://mlsanity.com/paper/2410.20327/) (2024)

## Built on by (most cited first, 3 of 3)

- [PathNavigate: A Training-Free Pathology Agent with Surprise-Guided Scan and Shared Slide Memory for Whole-Slide Image VQA](https://mlsanity.com/paper/2605.23559/) (2026)
- [The Path to Self-Evolving Clinical Systems: Scaling Medical Agents from Assistance to Autonomy](https://mlsanity.com/paper/2607.11175/) (2026)
- [MicroWorld: Empowering Multimodal Large Language Models to Bridge the Microscopic Domain Gap with Multimodal Attribute Graph](https://mlsanity.com/paper/2605.10120/) (2026)

## Abstract (arXiv)

Medical Visual Question Answering (MedVQA) enables natural language queries over medical images to support clinical decision-making and patient care. The MEDIQA-WV 2025 shared task addressed wound-care VQA, requiring systems to generate free-text responses and structured wound attributes from images and patient queries. We present the MasonNLP system, which employs a general-domain, instruction-tuned large language model with a retrieval-augmented generation (RAG) framework that incorporates textual and visual examples from in-domain data. This approach grounds outputs in clinically relevant exemplars, improving reasoning, schema adherence, and response quality across dBLEU, ROUGE, BERTScore, and LLM-based metrics. Our best-performing system ranked 3rd among 19 teams and 51 submissions with an average score of 41.37%, demonstrating that lightweight RAG with general-purpose LLMs -- a minimal inference-time layer that adds a few relevant exemplars via simple indexing and fusion, with no extra training or complex re-ranking -- provides a simple and effective baseline for multimodal clinical NLP tasks.