# Assessing the robustness of heterogeneous treatment effects in survival analysis under informative censoring

arXiv: https://arxiv.org/abs/2510.13397 · HTML: https://mlsanity.com/paper/2510.13397/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 45 of its 98 references that are in the map.
- First posted on arXiv 15 Oct 2025.

## Builds on (most cited first, 30 of 45)

- [DeepSurv: Personalized Treatment Recommender System Using A Cox Proportional Hazards Deep Neural Network](https://mlsanity.com/paper/1606.00931/) (2016)
- [Quasi-Oracle Estimation of Heterogeneous Treatment Effects](https://mlsanity.com/paper/1712.04912/) (2017)
- [Nonparametric Estimation of Heterogeneous Treatment Effects: From Theory to Learning Algorithms](https://mlsanity.com/paper/2101.10943/) (2021)
- [Semiparametric doubly robust targeted double machine learning: a review](https://mlsanity.com/paper/2203.06469/) (2022)
- [The Causal-Neural Connection: Expressiveness, Learnability, and Inference](https://mlsanity.com/paper/2107.00793/) (2021)
- [Deep Learning for Survival Analysis: A Review](https://mlsanity.com/paper/2305.14961/) (2023)
- [Sensitivity Analysis of Individual Treatment Effects: A Robust Conformal Inference Approach](https://mlsanity.com/paper/2111.12161/) (2021)
- [Neural Causal Models for Counterfactual Identification and Estimation](https://mlsanity.com/paper/2210.00035/) (2022)
- [Conformalized Survival Analysis](https://mlsanity.com/paper/2103.09763/) (2021)
- [Interval Estimation of Individual-Level Causal Effects Under Unobserved Confounding](https://mlsanity.com/paper/1810.02894/) (2018)
- [Quantifying Ignorance in Individual-Level Causal-Effect Estimates under Hidden Confounding](https://mlsanity.com/paper/2103.04850/) (2021)
- [An Automated Approach to Causal Inference in Discrete Settings](https://mlsanity.com/paper/2109.13471/) (2021)
- [The Influence Function of Semiparametric Estimators](https://mlsanity.com/paper/1508.01378/) (2015)
- [Sensitivity analysis for inverse probability weighting estimators via the percentile bootstrap](https://mlsanity.com/paper/1711.11286/) (2017)
- [Sharp Sensitivity Analysis for Inverse Propensity Weighting via Quantile Balancing](https://mlsanity.com/paper/2102.04543/) (2021)
- [Estimating heterogeneous treatment effects with right-censored data via causal survival forests](https://mlsanity.com/paper/2001.09887/) (2020)
- [A Class of Algorithms for General Instrumental Variable Models](https://mlsanity.com/paper/2006.06366/) (2020)
- [Doubly-Valid/Doubly-Sharp Sensitivity Analysis for Causal Inference with Unmeasured Confounding](https://mlsanity.com/paper/2112.11449/) (2021)
- [B-Learner: Quasi-Oracle Bounds on Heterogeneous Causal Effects Under Hidden Confounding](https://mlsanity.com/paper/2304.10577/) (2023)
- [SurvITE: Learning Heterogeneous Treatment Effects from Time-to-Event Data](https://mlsanity.com/paper/2110.14001/) (2021)
- [Stochastic Causal Programming for Bounding Treatment Effects](https://mlsanity.com/paper/2202.10806/) (2022)
- [Sharp Bounds for Generalized Causal Sensitivity Analysis](https://mlsanity.com/paper/2305.16988/) (2023)
- [Scalable Sensitivity and Uncertainty Analysis for Causal-Effect Estimates of Continuous-Valued Interventions](https://mlsanity.com/paper/2204.10022/) (2022)
- [Conformalized survival analysis with adaptive cutoffs](https://mlsanity.com/paper/2211.01227/) (2022)
- [A Neural Framework for Generalized Causal Sensitivity Analysis](https://mlsanity.com/paper/2311.16026/) (2023)
- [Individualized Treatment Effects with Censored Data via Fully Nonparametric Bayesian Accelerated Failure Time Models](https://mlsanity.com/paper/1706.06611/) (2017)
- [Estimating heterogeneous survival treatment effect in observational data using machine learning](https://mlsanity.com/paper/2008.07044/) (2020)
- [Sensitivity analysis under the f-sensitivity models: a distributional robustness perspective](https://mlsanity.com/paper/2203.04373/) (2022)
- [Meta-Learners for Partially-Identified Treatment Effects Across Multiple Environments](https://mlsanity.com/paper/2406.02464/) (2024)
- [Sensitivity Analysis for Marginal Structural Models](https://mlsanity.com/paper/2210.04681/) (2022)

## Built on by (most cited first, 1 of 1)

- [Causal Inference on Networks under Misspecified Exposure Mappings: A Partial Identification Framework](https://mlsanity.com/paper/2602.03459/) (2026)

## Abstract (arXiv)

Dropout is common in clinical studies, with up to half of patients leaving early due to side effects or other reasons. When dropout is informative (i.e., dependent on survival time), it introduces censoring bias, because of which treatment effect estimates are also biased. In this paper, we propose an assumption-lean framework to assess the robustness of conditional average treatment effect (CATE) estimates in survival analysis when facing censoring bias. Unlike existing works that rely on strong assumptions, such as non-informative censoring, to obtain point estimation, we use partial identification to derive informative bounds on the CATE. Thereby, our framework helps to identify patient subgroups where treatment is effective despite informative censoring. We further propose a novel model-agnostic meta-learner, called SurvB-learner, to estimate the bounds that can be used in combination with arbitrary machine-learning models, and that has favorable theoretical properties such as double-robustness and quasi-oracle efficiency. We finally demonstrate the effectiveness of our meta-learner across various experiments using both simulated and real-world data.
