# ViConEx-Med: Visual Concept Explainability via Multi-Concept Token Transformer for Medical Image Analysis

arXiv: https://arxiv.org/abs/2510.10174 · HTML: https://mlsanity.com/paper/2510.10174/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 25 of its 43 references that are in the map.
- First posted on arXiv 11 Oct 2025.

## Builds on (most cited first, 25 of 25)

- [Learning Deep Features for Discriminative Localization](https://mlsanity.com/paper/1512.04150/) (2015)
- [Interpretability Beyond Feature Attribution: Quantitative Testing with Concept Activation Vectors (TCAV)](https://mlsanity.com/paper/1711.11279/) (2017)
- [Concept Bottleneck Models](https://mlsanity.com/paper/2007.04612/) (2020)
- [Transformers in Vision: A Survey](https://mlsanity.com/paper/2101.01169/) (2021)
- [Going deeper with Image Transformers](https://mlsanity.com/paper/2103.17239/) (2021)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [Methods for Interpreting and Understanding Deep Neural Networks](https://mlsanity.com/paper/1706.07979/) (2017)
- [Visual Classification via Description from Large Language Models](https://mlsanity.com/paper/2210.07183/) (2022)
- [Top-down Neural Attention by Excitation Backprop](https://mlsanity.com/paper/1608.00507/) (2016)
- [Language in a Bottle: Language Model Guided Concept Bottlenecks for Interpretable Image Classification](https://mlsanity.com/paper/2211.11158/) (2022)
- [Label-Free Concept Bottleneck Models](https://mlsanity.com/paper/2304.06129/) (2023)
- [Quantus: An Explainable AI Toolkit for Responsible Evaluation of Neural Network Explanations and Beyond](https://mlsanity.com/paper/2202.06861/) (2022)
- [Multi-class Token Transformer for Weakly Supervised Semantic Segmentation](https://mlsanity.com/paper/2203.02891/) (2022)
- [MedViT: A Robust Vision Transformer for Generalized Medical Image Classification](https://mlsanity.com/paper/2302.09462/) (2023)
- [Leveraging Auxiliary Tasks with Affinity Learning for Weakly Supervised Semantic Segmentation](https://mlsanity.com/paper/2107.11787/) (2021)
- [A Multimodal Vision Foundation Model for Clinical Dermatology](https://mlsanity.com/paper/2410.15038/) (2024)
- [MedImageInsight: An Open-Source Embedding Model for General Domain Medical Imaging](https://mlsanity.com/paper/2410.06542/) (2024)
- [Robust and Interpretable Medical Image Classifiers via Concept Bottleneck Models](https://mlsanity.com/paper/2310.03182/) (2023)
- [On Interpretability of Deep Learning based Skin Lesion Classifiers using Concept Activation Vectors](https://mlsanity.com/paper/2005.02000/) (2020)
- [Explainable Deep Learning Methods in Medical Image Classification: A Survey](https://mlsanity.com/paper/2205.04766/) (2022)
- [Deep Learning Ensembles for Melanoma Recognition in Dermoscopy Images](https://mlsanity.com/paper/1610.04662/) (2016)
- [Coherent Concept-based Explanations in Medical Image and Its Application to Skin Lesion Diagnosis](https://mlsanity.com/paper/2304.04579/) (2023)
- [MCTformer+: Multi-Class Token Transformer for Weakly Supervised Semantic Segmentation](https://mlsanity.com/paper/2308.03005/) (2023)
- [MICA: Towards Explainable Skin Lesion Diagnosis via Multi-Level Image-Concept Alignment](https://mlsanity.com/paper/2401.08527/) (2024)
- [Towards Concept-based Interpretability of Skin Lesion Diagnosis using Vision-Language Models](https://mlsanity.com/paper/2311.14339/) (2023)

## Abstract (arXiv)

Concept-based models aim to explain model decisions with human-understandable concepts. However, most existing approaches treat concepts as numerical attributes, without providing complementary visual explanations that could localize the predicted concepts. This limits their utility in real-world applications and particularly in high-stakes scenarios, such as medical use-cases. This paper proposes ViConEx-Med, a novel transformer-based framework for visual concept explainability, which introduces multi-concept learnable tokens to jointly predict and localize visual concepts. By leveraging specialized attention layers for processing visual and text-based concept tokens, our method produces concept-level localization maps while maintaining high predictive accuracy. Experiments on both synthetic and real-world medical datasets demonstrate that ViConEx-Med outperforms prior concept-based models and achieves competitive performance with black-box models in terms of both concept detection and localization precision. Our results suggest a promising direction for building inherently interpretable models grounded in visual concepts. Code is publicly available at https://github.com/CristianoPatricio/viconex-med.
