# Toward Autonomous Soft Robotic Endovascular Navigation via Imitation Learning

arXiv: https://arxiv.org/abs/2510.09497 · HTML: https://mlsanity.com/paper/2510.09497/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Safe offline RL, one of 13 directions in Offline RL and imitation learning from data.
- Builds on 15 of its 44 references that are in the map.
- First posted on arXiv 10 Oct 2025.

## Placed in

- Offline RL and imitation learning from data / [Safe offline RL](https://mlsanity.com/offlinerl/safe-offline-rl/)

## Builds on (most cited first, 15 of 15)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [SAM 2: Segment Anything in Images and Videos](https://mlsanity.com/paper/2408.00714/) (2024)
- [Diffusion Policy: Visuomotor Policy Learning via Action Diffusion](https://mlsanity.com/paper/2303.04137/) (2023)
- [Learning Fine-Grained Bimanual Manipulation with Low-Cost Hardware](https://mlsanity.com/paper/2304.13705/) (2023)
- [What Matters in Learning from Offline Human Demonstrations for Robot Manipulation](https://mlsanity.com/paper/2108.03298/) (2021)
- [Learning by Cheating](https://mlsanity.com/paper/1912.12294/) (2019)
- [Value Iteration Networks](https://mlsanity.com/paper/1602.02867/) (2016)
- [Waypoint Models for Instruction-guided Navigation in Continuous Environments](https://mlsanity.com/paper/2110.02207/) (2021)
- [RT-Sketch: Goal-Conditioned Imitation Learning from Hand-Drawn Sketches](https://mlsanity.com/paper/2403.02709/) (2024)
- [Surgical Robot Transformer (SRT): Imitation Learning for Surgical Tasks](https://mlsanity.com/paper/2407.12998/) (2024)
- [SRT-H: A Hierarchical Framework for Autonomous Surgery via Language Conditioned Imitation Learning](https://mlsanity.com/paper/2505.10251/) (2025)
- [Data-driven Methods Applied to Soft Robot Modeling and Control: A Review](https://mlsanity.com/paper/2305.12137/) (2023)
- [Learning-Based Autonomous Navigation, Benchmark Environments and Simulation Framework for Endovascular Interventions](https://mlsanity.com/paper/2410.01956/) (2024)

## Built on by (most cited first, 1 of 1)

- [Autonomous Robotic Navigation for Endovascular Brain-Computer Interface Access](https://mlsanity.com/paper/2610.03537/) (2026)

## Abstract (arXiv)

In endovascular surgery, endovascular interventionists push a thin tube called a catheter, guided by a thin wire to a treatment site inside the patient's blood vessels to treat various conditions such as blood clots, aneurysms, and malformations. Robotic guidewires can enhance maneuverability but are difficult to model and control. Autonomous soft robotic guidewire navigation has the potential to overcome these challenges, increasing the precision and safety of endovascular navigation. As a first step, we establish a large-scale, 2D-projected environment for autonomous navigation. In other surgical domains, end-to-end imitation learning has shown promising results. Thus, we develop a transformer-based imitation learning framework with goal conditioning, relative action outputs, and automatic contrast dye injections to enable generalizable soft robot navigation in an aneurysm targeting task. We train the policy on 36 different modular bifurcated geometries, generating 647 total demonstrations under simulated fluoroscopy, and evaluate it on three previously unseen vascular geometries. The policy reaches the aneurysm with a success rate of 83% on the unseen geometries, outperforming several baselines. In addition, ablation and baseline studies evaluate the effectiveness of each design and data collection choice. Lastly, we extend the policy to achieve 75% success on an unseen patient-derived geometry. Project website: https://softrobotnavigation.github.io/