# FS-RWKV: Leveraging Frequency Spatial-Aware RWKV for 3T-to-7T MRI Translation

arXiv: https://arxiv.org/abs/2510.08951 · HTML: https://mlsanity.com/paper/2510.08951/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 15 of its 46 references that are in the map.
- First posted on arXiv 10 Oct 2025.

## Builds on (most cited first, 15 of 15)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [SGDR: Stochastic Gradient Descent with Warm Restarts](https://mlsanity.com/paper/1608.03983/) (2016)
- [Image-to-Image Translation with Conditional Adversarial Networks](https://mlsanity.com/paper/1611.07004/) (2016)
- [RWKV: Reinventing RNNs for the Transformer Era](https://mlsanity.com/paper/2305.13048/) (2023)
- [Transformers in Medical Imaging: A Survey](https://mlsanity.com/paper/2201.09873/) (2022)
- [Unsupervised Medical Image Translation with Adversarial Diffusion Models](https://mlsanity.com/paper/2207.08208/) (2022)
- [ResViT: Residual vision transformers for multi-modal medical image synthesis](https://mlsanity.com/paper/2106.16031/) (2021)
- [Image Synthesis in Multi-Contrast MRI with Conditional Generative Adversarial Networks](https://mlsanity.com/paper/1802.01221/) (2018)
- [Vision-RWKV: Efficient and Scalable Visual Perception with RWKV-Like Architectures](https://mlsanity.com/paper/2403.02308/) (2024)
- [Breaking the Dilemma of Medical Image-to-image Translation](https://mlsanity.com/paper/2110.06465/) (2021)
- [CoLa-Diff: Conditional Latent Diffusion Model for Multi-Modal MRI Synthesis](https://mlsanity.com/paper/2303.14081/) (2023)
- [Restore-RWKV: Efficient and Effective Medical Image Restoration with RWKV](https://mlsanity.com/paper/2407.11087/) (2024)
- [LSNet: See Large, Focus Small](https://mlsanity.com/paper/2503.23135/) (2025)
- [7T MRI Synthesization from 3T Acquisitions](https://mlsanity.com/paper/2403.08979/) (2024)
- [Multi-View Learning with Context-Guided Receptance for Image Denoising](https://mlsanity.com/paper/2505.02705/) (2025)

## Built on by (most cited first, 1 of 1)

- [HiP-LoRA: Budgeted Spectral Plasticity for Robust Low-Rank Adaptation](https://mlsanity.com/paper/2604.17751/) (2026)

## Abstract (arXiv)

Ultra-high-field 7T MRI offers enhanced spatial resolution and tissue contrast that enables the detection of subtle pathological changes in neurological disorders. However, the limited availability of 7T scanners restricts widespread clinical adoption due to substantial infrastructure costs and technical demands. Computational approaches for synthesizing 7T-quality images from accessible 3T acquisitions present a viable solution to this accessibility challenge. Existing CNN approaches suffer from limited spatial coverage, while Transformer models demand excessive computational overhead. RWKV architectures offer an efficient alternative for global feature modeling in medical image synthesis, combining linear computational complexity with strong long-range dependency capture. Building on this foundation, we propose Frequency Spatial-RWKV (FS-RWKV), an RWKV-based framework for 3T-to-7T MRI translation. To better address the challenges of anatomical detail preservation and global tissue contrast recovery, FS-RWKV incorporates two key modules: (1) Frequency-Spatial Omnidirectional Shift (FSO-Shift), which performs discrete wavelet decomposition followed by omnidirectional spatial shifting on the low-frequency branch to enhance global contextual representation while preserving high-frequency anatomical details; and (2) Structural Fidelity Enhancement Block (SFEB), a module that adaptively reinforces anatomical structure through frequency-aware feature fusion. Comprehensive experiments on UNC and BNU datasets demonstrate that FS-RWKV consistently outperforms existing CNN-, Transformer-, GAN-, and RWKV-based baselines across both T1w and T2w modalities, achieving superior anatomical fidelity and perceptual quality.