# A Data-Driven Prism: Multi-View Source Separation with Diffusion Model Priors

arXiv: https://arxiv.org/abs/2510.05205 · HTML: https://mlsanity.com/paper/2510.05205/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Placed in Inverse problems and image restoration, one of 14 directions in Diffusion models.
- Builds on 37 of its 74 references that are in the map.
- First posted on arXiv 6 Oct 2025.

## Placed in

- Diffusion models / [Inverse problems and image restoration](https://mlsanity.com/diffusion/inverse-problems-and-image-restoration/)

## Builds on (most cited first, 30 of 37)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [ImageNet Large Scale Visual Recognition Challenge](https://mlsanity.com/paper/1409.0575/) (2014)
- [Deep Unsupervised Learning using Nonequilibrium Thermodynamics](https://mlsanity.com/paper/1503.03585/) (2015)
- [Scalable Diffusion Models with Transformers](https://mlsanity.com/paper/2212.09748/) (2022)
- [Layer Normalization](https://mlsanity.com/paper/1607.06450/) (2016)
- [Generative Modeling by Estimating Gradients of the Data Distribution](https://mlsanity.com/paper/1907.05600/) (2019)
- [Improved Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2102.09672/) (2021)
- [Elucidating the Design Space of Diffusion-Based Generative Models](https://mlsanity.com/paper/2206.00364/) (2022)
- [Optuna: A Next-generation Hyperparameter Optimization Framework](https://mlsanity.com/paper/1907.10902/) (2019)
- [FiLM: Visual Reasoning with a General Conditioning Layer](https://mlsanity.com/paper/1709.07871/) (2017)
- [Diffusion Posterior Sampling for General Noisy Inverse Problems](https://mlsanity.com/paper/2209.14687/) (2022)
- [Denoising Diffusion Restoration Models](https://mlsanity.com/paper/2201.11793/) (2022)
- [Sigmoid-Weighted Linear Units for Neural Network Function Approximation in Reinforcement Learning](https://mlsanity.com/paper/1702.03118/) (2017)
- [Solving Inverse Problems in Medical Imaging with Score-Based Generative Models](https://mlsanity.com/paper/2111.08005/) (2021)
- [Denoising Diffusion Models for Plug-and-Play Image Restoration](https://mlsanity.com/paper/2305.08995/) (2023)
- [Compressed Sensing using Generative Models](https://mlsanity.com/paper/1703.03208/) (2017)
- [SNIPS: Solving Noisy Inverse Problems Stochastically](https://mlsanity.com/paper/2105.14951/) (2021)
- [A Survey on Diffusion Models for Inverse Problems](https://mlsanity.com/paper/2410.00083/) (2024)
- [Patch Diffusion: Faster and More Data-Efficient Training of Diffusion Models](https://mlsanity.com/paper/2304.12526/) (2023)
- [Score-Based Diffusion Models as Principled Priors for Inverse Imaging](https://mlsanity.com/paper/2304.11751/) (2023)
- [Wave-U-Net: A Multi-Scale Neural Network for End-to-End Audio Source Separation](https://mlsanity.com/paper/1806.03185/) (2018)
- [Invertible generative models for inverse problems: mitigating representation error and dataset bias](https://mlsanity.com/paper/1905.11672/) (2019)
- [Faster Wasserstein Distance Estimation with the Sinkhorn Divergence](https://mlsanity.com/paper/2006.08172/) (2020)
- [Learning Diffusion Priors from Observations by Expectation Maximization](https://mlsanity.com/paper/2405.13712/) (2024)
- [Solving Inverse Problems with a Flow-based Noise Model](https://mlsanity.com/paper/2003.08089/) (2020)

## Built on by (most cited first, 2 of 2)

- [StrADiff: A Structured Source-Wise Adaptive Diffusion Framework for Linear and Nonlinear Blind Source Separation](https://mlsanity.com/paper/2604.04973/) (2026)
- [Generative Models and Statistical Validation](https://mlsanity.com/paper/2605.30453/) (2026)

## Abstract (arXiv)

A common challenge in the natural sciences is to disentangle distinct, unknown sources from observations. Examples of this source separation task include deblending galaxies in a crowded field, distinguishing the activity of individual neurons from overlapping signals, and separating seismic events from an ambient background. Traditional analyses often rely on simplified source models that fail to accurately reproduce the data. Recent advances have shown that diffusion models can directly learn complex prior distributions from noisy, incomplete data. In this work, we show that diffusion models can solve the source separation problem without explicit assumptions about the source. Our method relies only on multiple views, or the property that different sets of observations contain different linear transformations of the unknown sources. We show that our method succeeds even when no source is individually observed and the observations are noisy, incomplete, and vary in resolution. The learned diffusion models enable us to sample from the source priors, evaluate the probability of candidate sources, and draw from the joint posterior of the source distribution given an observation. We demonstrate the effectiveness of our method on a range of synthetic problems as well as real-world galaxy observations.