# GDiffuSE: Diffusion-based speech enhancement with noise model guidance

arXiv: https://arxiv.org/abs/2510.04157 · HTML: https://mlsanity.com/paper/2510.04157/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Audio, speech and music, one of 14 directions in Diffusion models.
- Builds on 18 of its 33 references that are in the map.
- First posted on arXiv 5 Oct 2025.

## Placed in

- Diffusion models / [Audio, speech and music](https://mlsanity.com/diffusion/audio-speech-and-music/)

## Builds on (most cited first, 18 of 18)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [Deep Unsupervised Learning using Nonequilibrium Thermodynamics](https://mlsanity.com/paper/1503.03585/) (2015)
- [Elucidating the Design Space of Diffusion-Based Generative Models](https://mlsanity.com/paper/2206.00364/) (2022)
- [WaveNet: A Generative Model for Raw Audio](https://mlsanity.com/paper/1609.03499/) (2016)
- [DiffWave: A Versatile Diffusion Model for Audio Synthesis](https://mlsanity.com/paper/2009.09761/) (2020)
- [SDR - half-baked or well done?](https://mlsanity.com/paper/1811.02508/) (2018)
- [Applying Guidance in a Limited Interval Improves Sample and Distribution Quality in Diffusion Models](https://mlsanity.com/paper/2404.07724/) (2024)
- [DNSMOS: A Non-Intrusive Perceptual Objective Speech Quality metric to evaluate Noise Suppressors](https://mlsanity.com/paper/2010.15258/) (2020)
- [Supervised Speech Separation Based on Deep Learning: An Overview](https://mlsanity.com/paper/1708.07524/) (2017)
- [Speech Enhancement and Dereverberation with Diffusion-based Generative Models](https://mlsanity.com/paper/2208.05830/) (2022)
- [StoRM: A Diffusion-based Stochastic Regeneration Model for Speech Enhancement and Dereverberation](https://mlsanity.com/paper/2212.11851/) (2022)
- [Universal Speech Enhancement with Score-based Diffusion](https://mlsanity.com/paper/2206.03065/) (2022)
- [Analysis of Classifier-Free Guidance Weight Schedulers](https://mlsanity.com/paper/2404.13040/) (2024)
- [A Study on Speech Enhancement Based on Diffusion Probabilistic Model](https://mlsanity.com/paper/2107.11876/) (2021)
- [Unsupervised speech enhancement with diffusion-based generative models](https://mlsanity.com/paper/2309.10450/) (2023)
- [UnDiff: Unsupervised Voice Restoration with Unconditional Diffusion Model](https://mlsanity.com/paper/2306.00721/) (2023)

## Abstract (arXiv)

This paper introduces a novel speech enhancement (SE) approach based on a denoising diffusion probabilistic model (DDPM), termed Guided diffusion for speech enhancement (GDiffuSE). In contrast to conventional methods that directly map noisy speech to clean speech, our method employs a lightweight helper model to estimate the noise distribution, which is then incorporated into the diffusion denoising process via a guidance mechanism. This design improves robustness by enabling seamless adaptation to unseen noise types and by leveraging large-scale DDPMs originally trained for speech generation in the context of SE. We evaluate our approach on noisy signals obtained by adding noise samples from the BBC sound effects database to LibriSpeech utterances, showing consistent improvements over state-of-the-art baselines under mismatched noise conditions. Examples are available at our project webpage.