# Backdoor-Powered Prompt Injection Attacks Nullify Defense Methods

arXiv: https://arxiv.org/abs/2510.03705 · HTML: https://mlsanity.com/paper/2510.03705/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Placed in Prompt injection and agent security, one of 12 directions in LLM safety and security.
- Builds on 46 of its 64 references that are in the map.
- First posted on arXiv 4 Oct 2025.

## Placed in

- LLM safety and security / [Prompt injection and agent security](https://mlsanity.com/safety/prompt-injection-and-agent-security/)

## Builds on (most cited first, 30 of 46)

- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Evaluating Large Language Models Trained on Code](https://mlsanity.com/paper/2107.03374/) (2021)
- [Direct Preference Optimization: Your Language Model is Secretly a Reward Model](https://mlsanity.com/paper/2305.18290/) (2023)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Towards Deep Learning Models Resistant to Adversarial Attacks](https://mlsanity.com/paper/1706.06083/) (2017)
- [Large Language Models are Zero-Shot Reasoners](https://mlsanity.com/paper/2205.11916/) (2022)
- [Universal and Transferable Adversarial Attacks on Aligned Language Models](https://mlsanity.com/paper/2307.15043/) (2023)
- [ZeRO: Memory Optimizations Toward Training Trillion Parameter Models](https://mlsanity.com/paper/1910.02054/) (2019)
- [Ignore Previous Prompt: Attack Techniques For Language Models](https://mlsanity.com/paper/2211.09527/) (2022)
- [AlpacaFarm: A Simulation Framework for Methods that Learn from Human Feedback](https://mlsanity.com/paper/2305.14387/) (2023)
- [Prompt Injection attack against LLM-integrated Applications](https://mlsanity.com/paper/2306.05499/) (2023)
- [InjecAgent: Benchmarking Indirect Prompt Injections in Tool-Integrated Large Language Model Agents](https://mlsanity.com/paper/2403.02691/) (2024)
- [Sleeper Agents: Training Deceptive LLMs that Persist Through Safety Training](https://mlsanity.com/paper/2401.05566/) (2024)
- [The Instruction Hierarchy: Training LLMs to Prioritize Privileged Instructions](https://mlsanity.com/paper/2404.13208/) (2024)
- [StruQ: Defending Against Prompt Injection with Structured Queries](https://mlsanity.com/paper/2402.06363/) (2024)
- [Poisoning Web-Scale Training Datasets is Practical](https://mlsanity.com/paper/2302.10149/) (2023)
- [Poisoning Language Models During Instruction Tuning](https://mlsanity.com/paper/2305.00944/) (2023)
- [Defending Against Indirect Prompt Injection Attacks With Spotlighting](https://mlsanity.com/paper/2403.14720/) (2024)
- [Benchmarking and Defending Against Indirect Prompt Injection Attacks on Large Language Models](https://mlsanity.com/paper/2312.14197/) (2023)
- [ONION: A Simple and Effective Defense Against Textual Backdoor Attacks](https://mlsanity.com/paper/2011.10369/) (2020)
- [Backdooring Instruction-Tuned Large Language Models with Virtual Prompt Injection](https://mlsanity.com/paper/2307.16888/) (2023)
- [Tensor Trust: Interpretable Prompt Injection Attacks from an Online Game](https://mlsanity.com/paper/2311.01011/) (2023)
- [Optimization-based Prompt Injection Attack to LLM-as-a-Judge](https://mlsanity.com/paper/2403.17710/) (2024)
- [BadAgent: Inserting and Activating Backdoor Attacks in LLM Agents](https://mlsanity.com/paper/2406.03007/) (2024)
- [Jatmo: Prompt Injection Defense by Task-Specific Finetuning](https://mlsanity.com/paper/2312.17673/) (2023)
- [Machine Against the RAG: Jamming Retrieval-Augmented Generation with Blocker Documents](https://mlsanity.com/paper/2406.05870/) (2024)
- [BadGPT: Exploring Security Vulnerabilities of ChatGPT via Backdoor Attacks to InstructGPT](https://mlsanity.com/paper/2304.12298/) (2023)
- [UniGraph: Learning a Unified Cross-Domain Foundation Model for Text-Attributed Graphs](https://mlsanity.com/paper/2402.13630/) (2024)
- [Safety in Large Reasoning Models: A Survey](https://mlsanity.com/paper/2504.17704/) (2025)
- [Efficient Inference for Large Reasoning Models: A Survey](https://mlsanity.com/paper/2503.23077/) (2025)

## Built on by (most cited first, 3 of 3)

- [WARD: Adversarially Robust Defense of Web Agents Against Prompt Injections](https://mlsanity.com/paper/2605.15030/) (2026)
- [WebAgentGuard: A Reasoning-Driven Guard Model for Detecting Prompt Injection Attacks in Web Agents](https://mlsanity.com/paper/2604.12284/) (2026)
- [Large Language Models for Agentic NetOps and AIOps: Architectures, Evaluation, and Safety](https://mlsanity.com/paper/2605.12729/) (2026)

## Abstract (arXiv)

With the development of technology, large language models (LLMs) have dominated the downstream natural language processing (NLP) tasks. However, because of the LLMs' instruction-following abilities and inability to distinguish the instructions in the data content, such as web pages from search engines, the LLMs are vulnerable to prompt injection attacks. These attacks trick the LLMs into deviating from the original input instruction and executing the attackers' target instruction. Recently, various instruction hierarchy defense strategies are proposed to effectively defend against prompt injection attacks via fine-tuning. In this paper, we explore more vicious attacks that nullify the prompt injection defense methods, even the instruction hierarchy: backdoor-powered prompt injection attacks, where the attackers utilize the backdoor attack for prompt injection attack purposes. Specifically, the attackers poison the supervised fine-tuning samples and insert the backdoor into the model. Once the trigger is activated, the backdoored model executes the injected instruction surrounded by the trigger. We construct a benchmark for comprehensive evaluation. Our experiments demonstrate that backdoor-powered prompt injection attacks are more harmful than previous prompt injection attacks, nullifying existing prompt injection defense methods, even the instruction hierarchy techniques.