# ELPG-DTFS: Prior-Guided Adaptive Time-Frequency Graph Neural Network for EEG Depression Diagnosis

arXiv: https://arxiv.org/abs/2509.24860 · HTML: https://mlsanity.com/paper/2509.24860/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 2 of its 33 references that are in the map.
- First posted on arXiv 29 Sep 2025.

## Builds on (most cited first, 2 of 2)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Graph Pooling via Coarsened Graph Infomax](https://mlsanity.com/paper/2105.01275/) (2021)

## Abstract (arXiv)

Timely and objective screening of major depressive disorder (MDD) is vital, yet diagnosis still relies on subjective scales. Electroencephalography (EEG) provides a low-cost biomarker, but existing deep models treat spectra as static images, fix inter-channel graphs, and ignore prior knowledge, limiting accuracy and interpretability. We propose ELPG-DTFS, a prior-guided adaptive time-frequency graph neural network that introduces: (1) channel-band attention with cross-band mutual information, (2) a learnable adjacency matrix for dynamic functional links, and (3) a residual knowledge-graph pathway injecting neuroscience priors. On the 128-channel MODMA dataset (53 subjects), ELPG-DTFS achieves 97.63% accuracy and 97.33% F1, surpassing the 2025 state-of-the-art ACM-GNN. Ablation shows that removing any module lowers F1 by up to 4.35, confirming their complementary value. ELPG-DTFS thus offers a robust and interpretable framework for next-generation EEG-based MDD diagnostics.