# A Self-Adaptive Frequency Domain Network for Continuous Intraoperative Hypotension Prediction

arXiv: https://arxiv.org/abs/2509.23720 · HTML: https://mlsanity.com/paper/2509.23720/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 7 of its 26 references that are in the map.
- First posted on arXiv 28 Sep 2025.

## Builds on (most cited first, 7 of 7)

- [Informer: Beyond Efficient Transformer for Long Sequence Time-Series Forecasting](https://mlsanity.com/paper/2012.07436/) (2020)
- [Autoformer: Decomposition Transformers with Auto-Correlation for Long-Term Series Forecasting](https://mlsanity.com/paper/2106.13008/) (2021)
- [FEDformer: Frequency Enhanced Decomposed Transformer for Long-term Series Forecasting](https://mlsanity.com/paper/2201.12740/) (2022)
- [Anomaly Transformer: Time Series Anomaly Detection with Association Discrepancy](https://mlsanity.com/paper/2110.02642/) (2021)
- [Graph Neural Network-Based Anomaly Detection in Multivariate Time Series](https://mlsanity.com/paper/2106.06947/) (2021)
- [Frequency-domain MLPs are More Effective Learners in Time Series Forecasting](https://mlsanity.com/paper/2311.06184/) (2023)
- [MEMTO: Memory-guided Transformer for Multivariate Time Series Anomaly Detection](https://mlsanity.com/paper/2312.02530/) (2023)

## Abstract (arXiv)

Intraoperative hypotension (IOH) is strongly associated with postoperative complications, including postoperative delirium and increased mortality, making its early prediction crucial in perioperative care. While several artificial intelligence-based models have been developed to provide IOH warnings, existing methods face limitations in incorporating both time and frequency domain information, capturing short- and long-term dependencies, and handling noise sensitivity in biosignal data. To address these challenges, we propose a novel Self-Adaptive Frequency Domain Network (SAFDNet). Specifically, SAFDNet integrates an adaptive spectral block, which leverages Fourier analysis to extract frequency-domain features and employs self-adaptive thresholding to mitigate noise. Additionally, an interactive attention block is introduced to capture both long-term and short-term dependencies in the data. Extensive internal and external validations on two large-scale real-world datasets demonstrate that SAFDNet achieves up to 97.3% AUROC in IOH early warning, outperforming state-of-the-art models. Furthermore, SAFDNet exhibits robust predictive performance and low sensitivity to noise, making it well-suited for practical clinical applications.