# Manifold-Aware Diffusion-Augmented Contrastive Learning for Noise-Robust Biosignal Representation

arXiv: https://arxiv.org/abs/2509.20048 · HTML: https://mlsanity.com/paper/2509.20048/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 15 of its 25 references that are in the map.
- First posted on arXiv 24 Sep 2025.

## Builds on (most cited first, 15 of 15)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Momentum Contrast for Unsupervised Visual Representation Learning](https://mlsanity.com/paper/1911.05722/) (2019)
- [Deep Unsupervised Learning using Nonequilibrium Thermodynamics](https://mlsanity.com/paper/1503.03585/) (2015)
- [A Survey on Contrastive Self-supervised Learning](https://mlsanity.com/paper/2011.00362/) (2020)
- [TS2Vec: Towards Universal Representation of Time Series](https://mlsanity.com/paper/2106.10466/) (2021)
- [Time-Series Representation Learning via Temporal and Contextual Contrasting](https://mlsanity.com/paper/2106.14112/) (2021)
- [Diffusion Hyperfeatures: Searching Through Time and Space for Semantic Correspondence](https://mlsanity.com/paper/2305.14334/) (2023)
- [Data Augmentation of Wearable Sensor Data for Parkinson's Disease Monitoring using Convolutional Neural Networks](https://mlsanity.com/paper/1706.00527/) (2017)
- [MINA: Multilevel Knowledge-Guided Attention for Modeling Electrocardiography Signals](https://mlsanity.com/paper/1905.11333/) (2019)
- [Automated Identication of Atrial Fibrillation from Single-lead ECGs Using Multi-branching ResNet](https://mlsanity.com/paper/2306.15096/) (2023)
- [DiffCL: A Diffusion-Based Contrastive Learning Framework with Semantic Alignment for Multimodal Recommendations](https://mlsanity.com/paper/2501.01066/) (2025)
- [ASD-Diffusion: Anomalous Sound Detection with Diffusion Models](https://mlsanity.com/paper/2409.15957/) (2024)
- [Scattering Transformer: A Training-Free Transformer Architecture for Heart Murmur Detection](https://mlsanity.com/paper/2509.18424/) (2025)

## Abstract (arXiv)

Learning robust representations for physiological time-series signals continues to pose a substantial challenge in developing efficient few-shot learning applications. This difficulty is largely due to the complex pathological variations in biosignals. In this context, this paper introduces a manifold-aware Diffusion-Augmented Contrastive Learning (DACL) framework, which efficiently leverages the generative structure of latent diffusion models with the discriminative power of supervised contrastive learning. The proposed framework operates within a contextualized scattering latent space derived from Scattering Transformer (ST) features. Within a contrastive learning framework, we employ a forward diffusion process in the scattering latent space as a structured manifold-aware feature augmentation technique. We assessed the proposed framework using the PhysioNet 2017 ECG benchmark dataset. The proposed method achieved a competitive AUROC of 0.9741 in the task of detecting atrial fibrillation from a single-lead ECG signal. The proposed framework achieved performance on par with relevant state-of-the-art related works. In-depth evaluation findings suggest that early-stage diffusion serves as an ideal "local manifold explorer," producing embeddings with greater precision than typical augmentation methods while preserving inference efficiency.