# Visual Instruction Pretraining for Domain-Specific Foundation Models

arXiv: https://arxiv.org/abs/2509.17562 · HTML: https://mlsanity.com/paper/2509.17562/

## Key facts

- Cited by 9 papers in the map (data through 14 Oct 2026).
- Builds on 152 of its 202 references that are in the map.
- First posted on arXiv 22 Sep 2025.

## Builds on (most cited first, 30 of 152)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [DINOv2: Learning Robust Visual Features without Supervision](https://mlsanity.com/paper/2304.07193/) (2023)
- [Visual Instruction Tuning](https://mlsanity.com/paper/2304.08485/) (2023)
- [Momentum Contrast for Unsupervised Visual Representation Learning](https://mlsanity.com/paper/1911.05722/) (2019)
- [End-to-End Object Detection with Transformers](https://mlsanity.com/paper/2005.12872/) (2020)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [Mask R-CNN](https://mlsanity.com/paper/1703.06870/) (2017)
- [Qwen2.5-VL Technical Report](https://mlsanity.com/paper/2502.13923/) (2025)
- [Feature Pyramid Networks for Object Detection](https://mlsanity.com/paper/1612.03144/) (2016)
- [Bootstrap your own latent: A new approach to self-supervised Learning](https://mlsanity.com/paper/2006.07733/) (2020)
- [FlashAttention: Fast and Memory-Efficient Exact Attention with IO-Awareness](https://mlsanity.com/paper/2205.14135/) (2022)
- [Deformable DETR: Deformable Transformers for End-to-End Object Detection](https://mlsanity.com/paper/2010.04159/) (2020)
- [Qwen Technical Report](https://mlsanity.com/paper/2309.16609/) (2023)
- [Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1802.02611/) (2018)
- [Sigmoid Loss for Language Image Pre-Training](https://mlsanity.com/paper/2303.15343/) (2023)
- [SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformers](https://mlsanity.com/paper/2105.15203/) (2021)
- [LLaVA-OneVision: Easy Visual Task Transfer](https://mlsanity.com/paper/2408.03326/) (2024)
- [InternVL: Scaling up Vision Foundation Models and Aligning for Generic Visual-Linguistic Tasks](https://mlsanity.com/paper/2312.14238/) (2023)
- [Pyramid Scene Parsing Network](https://mlsanity.com/paper/1612.01105/) (2016)
- [BEiT: BERT Pre-Training of Image Transformers](https://mlsanity.com/paper/2106.08254/) (2021)
- [Masked-attention Mask Transformer for Universal Image Segmentation](https://mlsanity.com/paper/2112.01527/) (2021)
- [An Empirical Study of Training Self-Supervised Vision Transformers](https://mlsanity.com/paper/2104.02057/) (2021)

## Built on by (most cited first, 9 of 9)

- [UniChange: Unifying Change Detection with Multimodal Large Language Model](https://mlsanity.com/paper/2511.02607/) (2025)
- [CrystaL: Spontaneous Emergence of Visual Latents in MLLMs](https://mlsanity.com/paper/2602.20980/) (2026)
- [NAIPv2: Debiased Pairwise Learning for Efficient Paper Quality Estimation](https://mlsanity.com/paper/2509.25179/) (2025)
- [Unifying Heterogeneous Multi-Modal Remote Sensing Detection Via Language-Pivoted Pretraining](https://mlsanity.com/paper/2603.01758/) (2026)
- [SLIP-RS: Structured-Attribute Language-Image Pre-Training for Remote Sensing Object Detection](https://mlsanity.com/paper/2605.23144/) (2026)
- [VIVID-Med: LLM-Supervised Structured Pretraining for Deployable Medical ViTs](https://mlsanity.com/paper/2603.09109/) (2026)
- [WOW-Seg: A Word-free Open World Segmentation Model](https://mlsanity.com/paper/2605.16903/) (2026)
- [SARATR-X-v2: Scale-Aware Structural Pre-Training for SAR Foundation Models](https://mlsanity.com/paper/2607.23238/) (2026)
- [WinARDet: Compressed Window Auto-Regression for Long-Horizon Vision-Language Grounding](https://mlsanity.com/paper/2610.19419/) (2026)

## Abstract (arXiv)

Modern computer vision is converging on a closed loop in which perception, reasoning and generation mutually reinforce each other. However, this loop remains incomplete: the top-down influence of high-level reasoning on the foundational learning of low-level perceptual features is not yet underexplored. This paper addresses this gap by proposing a new paradigm for pretraining foundation models in downstream domains. We introduce Visual insTruction Pretraining (ViTP), a novel approach that directly leverages reasoning to enhance perception. ViTP embeds a Vision Transformer (ViT) backbone within a Vision-Language Model and pretrains it end-to-end using a rich corpus of visual instruction data curated from target downstream domains. ViTP is powered by our proposed Visual Robustness Learning (VRL), which compels the ViT to learn robust and domain-relevant features from a sparse set of visual tokens. Extensive experiments on 16 challenging remote sensing and medical imaging benchmarks demonstrate that ViTP establishes new state-of-the-art performance across a diverse range of downstream tasks. The code is available at https://github.com/zcablii/ViTP.