# Generalizability of Large Language Model-Based Agents: A Comprehensive Survey

arXiv: https://arxiv.org/abs/2509.16330 · HTML: https://mlsanity.com/paper/2509.16330/

## Key facts

- Cited by 10 papers in the map (data through 14 Oct 2026).
- Placed in General LLM agent frameworks and benchmarks, one of 16 directions in LLM agents and tool use.
- Builds on 94 of its 137 references that are in the map.
- First posted on arXiv 19 Sep 2025.

## Placed in

- LLM agents and tool use / [General LLM agent frameworks and benchmarks](https://mlsanity.com/agents/general-llm-agent-frameworks-and-benchmarks/)

## Builds on (most cited first, 30 of 94)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Training language models to follow instructions with human feedback](https://mlsanity.com/paper/2203.02155/) (2022)
- [Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformer](https://mlsanity.com/paper/1910.10683/) (2019)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [Toolformer: Language Models Can Teach Themselves to Use Tools](https://mlsanity.com/paper/2302.04761/) (2023)
- [Robust Speech Recognition via Large-Scale Weak Supervision](https://mlsanity.com/paper/2212.04356/) (2022)
- [Training a Helpful and Harmless Assistant with Reinforcement Learning from Human Feedback](https://mlsanity.com/paper/2204.05862/) (2022)
- [Self-Refine: Iterative Refinement with Self-Feedback](https://mlsanity.com/paper/2303.17651/) (2023)
- [Learning to summarize from human feedback](https://mlsanity.com/paper/2009.01325/) (2020)
- [The Pile: An 800GB Dataset of Diverse Text for Language Modeling](https://mlsanity.com/paper/2101.00027/) (2020)
- [WebArena: A Realistic Web Environment for Building Autonomous Agents](https://mlsanity.com/paper/2307.13854/) (2023)
- [ToolLLM: Facilitating Large Language Models to Master 16000+ Real-world APIs](https://mlsanity.com/paper/2307.16789/) (2023)
- [Self-RAG: Learning to Retrieve, Generate, and Critique through Self-Reflection](https://mlsanity.com/paper/2310.11511/) (2023)
- [The Rise and Potential of Large Language Model Based Agents: A Survey](https://mlsanity.com/paper/2309.07864/) (2023)
- [CAMEL: Communicative Agents for "Mind" Exploration of Large Language Model Society](https://mlsanity.com/paper/2303.17760/) (2023)
- [WebShop: Towards Scalable Real-World Web Interaction with Grounded Language Agents](https://mlsanity.com/paper/2207.01206/) (2022)
- [Mind2Web: Towards a Generalist Agent for the Web](https://mlsanity.com/paper/2306.06070/) (2023)
- [ALFWorld: Aligning Text and Embodied Environments for Interactive Learning](https://mlsanity.com/paper/2010.03768/) (2020)
- [OSWorld: Benchmarking Multimodal Agents for Open-Ended Tasks in Real Computer Environments](https://mlsanity.com/paper/2404.07972/) (2024)
- [ALFRED: A Benchmark for Interpreting Grounded Instructions for Everyday Tasks](https://mlsanity.com/paper/1912.01734/) (2019)
- [Whose Opinions Do Language Models Reflect?](https://mlsanity.com/paper/2303.17548/) (2023)
- [Open Problems and Fundamental Limitations of Reinforcement Learning from Human Feedback](https://mlsanity.com/paper/2307.15217/) (2023)
- [AudioLM: a Language Modeling Approach to Audio Generation](https://mlsanity.com/paper/2209.03143/) (2022)
- [Executable Code Actions Elicit Better LLM Agents](https://mlsanity.com/paper/2402.01030/) (2024)
- [GPT-4V(ision) is a Generalist Web Agent, if Grounded](https://mlsanity.com/paper/2401.01614/) (2024)
- [InjecAgent: Benchmarking Indirect Prompt Injections in Tool-Integrated Large Language Model Agents](https://mlsanity.com/paper/2403.02691/) (2024)
- [Reinforced Self-Training (ReST) for Language Modeling](https://mlsanity.com/paper/2308.08998/) (2023)
- [Dynabench: Rethinking Benchmarking in NLP](https://mlsanity.com/paper/2104.14337/) (2021)
- [Mixture-of-Agents Enhances Large Language Model Capabilities](https://mlsanity.com/paper/2406.04692/) (2024)

## Built on by (most cited first, 10 of 10)

- [DIVE: Scaling Diversity in Agentic Task Synthesis for Generalizable Tool Use](https://mlsanity.com/paper/2603.11076/) (2026)
- [OneDayAgent: Towards a Long-Horizon Harness for Autonomous Agents](https://mlsanity.com/paper/2608.05013/) (2026)
- [Consolidation or Adaptation? PRISM: Disentangling SFT and RL Data via Gradient Concentration](https://mlsanity.com/paper/2601.07224/) (2026)
- [Do LLMs Truly Generalize in the Molecular Domain? A Perturbation-Based Analysis](https://mlsanity.com/paper/2607.01800/) (2026)
- [MPCEval: A Benchmark for Multi-Party Conversation Generation](https://mlsanity.com/paper/2603.04969/) (2026)
- [Asymmetric Capacity Allocation in Self-Refinement Pipelines](https://mlsanity.com/paper/2608.21345/) (2026)
- [Resource Constraints and Performance in Agentic AI Systems](https://mlsanity.com/paper/2608.27886/) (2026)
- [Personalizing LLM Agent Memory Using Biometrics](https://mlsanity.com/paper/2609.08558/) (2026)
- [Behavior Quotient Learning for Low-Rank Adaptation of LLM Agents](https://mlsanity.com/paper/2609.12896/) (2026)
- [EVOKE: Eliciting World Knowledge in Agents for Transferable Decision-Making](https://mlsanity.com/paper/2609.38334/) (2026)

## Abstract (arXiv)

Large Language Model (LLM)-based agents have emerged as a new paradigm that extends LLMs' capabilities beyond text generation to dynamic interaction with external environments. By integrating reasoning with perception, memory, and tool use, agents are increasingly deployed in diverse domains like web navigation and household robotics. A critical challenge, however, lies in ensuring agent generalizability - the ability to maintain consistent performance across varied instructions, tasks, environments, and domains, especially those beyond agents' fine-tuning data. Despite growing interest, the concept of generalizability in LLM-based agents remains underdefined, and systematic approaches to measure and improve it are lacking. In this survey, we provide the first comprehensive review of generalizability in LLM-based agents. We begin by emphasizing agent generalizability's importance by appealing to stakeholders and clarifying the boundaries of agent generalizability by situating it within a hierarchical domain-task ontology. We then review datasets, evaluation dimensions, and metrics, highlighting their limitations. Next, we categorize methods for improving generalizability into three groups: methods for the backbone LLM, for agent components, and for their interactions. Moreover, we introduce the distinction between generalizable frameworks and generalizable agents and outline how generalizable frameworks can be translated into agent-level generalizability. Finally, we identify critical challenges and future directions, including developing standardized frameworks, variance- and cost-based metrics, and approaches that integrate methodological innovations with architecture-level designs. By synthesizing progress and highlighting opportunities, this survey aims to establish a foundation for principled research on building LLM-based agents that generalize reliably across diverse applications.