# AISSISTANT: Human-AI Collaborative Review and Perspective Research Workflows in Data Science

arXiv: https://arxiv.org/abs/2509.12282 · HTML: https://mlsanity.com/paper/2509.12282/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 18 of its 25 references that are in the map.
- First posted on arXiv 14 Sep 2025.

## Builds on (most cited first, 18 of 18)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [SWE-bench: Can Language Models Resolve Real-World GitHub Issues?](https://mlsanity.com/paper/2310.06770/) (2023)
- [π0: A Vision-Language-Action Flow Model for General Robot Control](https://mlsanity.com/paper/2410.24164/) (2024)
- [Mind2Web: Towards a Generalist Agent for the Web](https://mlsanity.com/paper/2306.06070/) (2023)
- [The AI Scientist: Towards Fully Automated Open-Ended Scientific Discovery](https://mlsanity.com/paper/2408.06292/) (2024)
- [OpenHands: An Open Platform for AI Software Developers as Generalist Agents](https://mlsanity.com/paper/2407.16741/) (2024)
- [ChemCrow: Augmenting large-language models with chemistry tools](https://mlsanity.com/paper/2304.05376/) (2023)
- [Agent Laboratory: Using LLM Agents as Research Assistants](https://mlsanity.com/paper/2501.04227/) (2025)
- [The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Search](https://mlsanity.com/paper/2504.08066/) (2025)
- [Can LLMs Generate Novel Research Ideas? A Large-Scale Human Study with 100+ NLP Researchers](https://mlsanity.com/paper/2409.04109/) (2024)
- [AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environments](https://mlsanity.com/paper/2405.07960/) (2024)
- [CycleResearcher: Improving Automated Research via Automated Review](https://mlsanity.com/paper/2411.00816/) (2024)
- [Towards Accurate Differential Diagnosis with Large Language Models](https://mlsanity.com/paper/2312.00164/) (2023)
- [HoneyComb: A Flexible LLM-Based Agent System for Materials Science](https://mlsanity.com/paper/2409.00135/) (2024)
- [SCI-IDEA: Context-Aware Scientific Ideation Using Token and Sentence Embeddings](https://mlsanity.com/paper/2503.19257/) (2025)
- [Shared Imagination: LLMs Hallucinate Alike](https://mlsanity.com/paper/2407.16604/) (2024)
- [AI Language Models Could Both Help and Harm Equity in Marine Policymaking: The Case Study of the BBNJ Question-Answering Bot](https://mlsanity.com/paper/2403.01755/) (2024)

## Built on by (most cited first, 1 of 1)

- [AutoResearchClaw: Self-Reinforcing Autonomous Research with Human-AI Collaboration](https://mlsanity.com/paper/2605.20025/) (2026)

## Abstract (arXiv)

High-quality scientific review and perspective papers require substantial time and effort, limiting researchers' ability to synthesize emerging knowledge. While Large Language Models (LLMs) leverage AI Scientists for scientific workflows, existing frameworks focus primarily on autonomous workflows with very limited human intervention. We introduce AIssistant, the first open-source agentic framework for Human--AI collaborative generation of scientific perspectives and review research in data science. AIssistant employs specialized LLM-driven agents augmented with external scholarly tools and allows human intervention throughout the workflow. The framework consists of two main multi-agent systems: Research Workflow with seven agents and a Paper Writing Workflow with eight agents. We conducted a comprehensive evaluation with both human expert reviewers and LLM-based assessment following NeurIPS standards. Our experiments show that OpenAI o1 achieves the highest quality scores on chain-of-thought prompting with augmented Literature Search tools. We also conducted a Human--AI interaction survey with results showing a 65.7% time savings. We believe that our work establishes a baseline for Human--AI collaborative scientific workflow for review and perspective research in data science, demonstrating that agent-augmented pipelines substantially reduce effort while maintaining research integrity through strategic human oversight.