# End-to-End 4D Heart Mesh Recovery Across Full-Stack and Sparse Cardiac MRI

arXiv: https://arxiv.org/abs/2509.12090 · HTML: https://mlsanity.com/paper/2509.12090/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- Builds on 20 of its 53 references that are in the map.
- First posted on arXiv 15 Sep 2025.

## Builds on (most cited first, 20 of 20)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Learning Phrase Representations using RNN Encoder-Decoder for Statistical Machine Translation](https://mlsanity.com/paper/1406.1078/) (2014)
- [Deep Marching Tetrahedra: a Hybrid Representation for High-Resolution 3D Shape Synthesis](https://mlsanity.com/paper/2111.04276/) (2021)
- [Voxel2Mesh: 3D Mesh Model Generation from Volumetric Data](https://mlsanity.com/paper/1912.03681/) (2019)
- [Joint Learning of Motion Estimation and Segmentation for Cardiac MR Image Sequences](https://mlsanity.com/paper/1806.04066/) (2018)
- [A Deep-Learning Approach For Direct Whole-Heart Mesh Reconstruction](https://mlsanity.com/paper/2102.07899/) (2021)
- [DeepCSR: A 3D Deep Learning Approach for Cortical Surface Reconstruction](https://mlsanity.com/paper/2010.11423/) (2020)
- [Vox2Cortex: Fast Explicit Reconstruction of Cortical Surfaces from 3D MRI Scans with Geometric Deep Neural Networks](https://mlsanity.com/paper/2203.09446/) (2022)
- [Biomechanics-informed Neural Networks for Myocardial Motion Tracking in MRI](https://mlsanity.com/paper/2006.04725/) (2020)
- [Real-time Cardiovascular MR with Spatio-temporal Artifact Suppression using Deep Learning - Proof of Concept in Congenital Heart Disease](https://mlsanity.com/paper/1803.05192/) (2018)
- [A personalized time-resolved 3D mesh generative model for unveiling normal heart dynamics](https://mlsanity.com/paper/2409.13825/) (2024)
- [MulViMotion: Shape-aware 3D Myocardial Motion Tracking from Multi-View Cardiac MRI](https://mlsanity.com/paper/2208.00034/) (2022)
- [4D Myocardium Reconstruction with Decoupled Motion and Shape Model](https://mlsanity.com/paper/2308.14083/) (2023)
- [DeepMesh: Mesh-based Cardiac Motion Tracking using Deep Learning](https://mlsanity.com/paper/2309.14306/) (2023)
- [Solving the Inverse Problem of Electrocardiography for Cardiac Digital Twins: A Survey](https://mlsanity.com/paper/2406.11445/) (2024)
- [Mesh-based 3D Motion Tracking in Cardiac MRI using Deep Learning](https://mlsanity.com/paper/2209.02004/) (2022)
- [Neural Deformable Models for 3D Bi-Ventricular Heart Shape Reconstruction and Modeling from 2D Sparse Cardiac Magnetic Resonance Imaging](https://mlsanity.com/paper/2307.07693/) (2023)
- [A Generative Shape Compositional Framework to Synthesise Populations of Virtual Chimaeras](https://mlsanity.com/paper/2210.01607/) (2022)

## Built on by (most cited first, 6 of 6)

- [From 2D to 3D, Deep Learning-based Shape Reconstruction in Magnetic Resonance Imaging: A Review](https://mlsanity.com/paper/2510.01296/) (2025)
- [Learning to Beat: Phenotype-Guided Latent Flow with Regional Motion Priors for Biventricular Motion Synthesis](https://mlsanity.com/paper/2608.19738/) (2026)
- [MRI-Guided Reslice-Refined Cross-Slice SDF Reconstruction of the Left Ventricle from Cardiac MRI with Sparse Axial Supervision](https://mlsanity.com/paper/2609.08148/) (2026)
- [Anatomy-Aligned Surface Field Learning for Myocardial Reconstruction from Sparse Short-Axis Cine MRI](https://mlsanity.com/paper/2609.29825/) (2026)
- [Local2Mesh: Spatially Localized Contour-to-Mesh for Left Ventricular Reconstruction from Sparse 2D Cardiac MRI](https://mlsanity.com/paper/2610.06052/) (2026)
- [Focus, Align, and Diffuse: Time-Series-Aware Keyframe Diffusion for Cardiac Dynamic Synthesis from Sparse Observations](https://mlsanity.com/paper/2610.19050/) (2026)

## Abstract (arXiv)

Reconstructing cardiac motion from CMR sequences is critical for diagnosis, prognosis, and intervention. Existing methods rely on complete CMR stacks to infer full heart motion, limiting their applicability during intervention when only sparse observations are available. We present TetHeart, the first end-to-end framework for unified 4D heart mesh recovery from both offline full-stack and intra-procedural sparse-slice observations. Our method leverages deformable tetrahedra to capture shape and motion in a coherent space shared across cardiac structures. Before a procedure, it initializes detailed, patient-specific heart meshes from high-quality full stacks, which can then be updated using whatever slices can be obtained in real-time, down to a single one during the procedure. TetHeart incorporates several key innovations: (i) an attentive slice-adaptive 2D-3D feature assembly mechanism that integrates information from arbitrary numbers of slices at any position; (ii) a distillation strategy to ensure accurate reconstruction under extreme sparsity; and (iii) a weakly supervised motion learning scheme requiring annotations only at keyframes, such as the end-diastolic and end-systolic phases. Trained and validated on three large public datasets and evaluated zero-shot on additional private interventional and public datasets without retraining, TetHeart achieves state-of-the-art accuracy and strong generalization in both pre- and intra-procedural settings. Code and dataset is available at https://github.com/Scalsol/TetHeart.
