# GLAM: Geometry-Guided Local Alignment for Multi-View VLP in Mammography

arXiv: https://arxiv.org/abs/2509.10344 · HTML: https://mlsanity.com/paper/2509.10344/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 17 of its 36 references that are in the map.
- First posted on arXiv 12 Sep 2025.

## Builds on (most cited first, 17 of 17)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [DINOv2: Learning Robust Visual Features without Supervision](https://mlsanity.com/paper/2304.07193/) (2023)
- [Publicly Available Clinical BERT Embeddings](https://mlsanity.com/paper/1904.03323/) (2019)
- [Contrastive Learning of Medical Visual Representations from Paired Images and Text](https://mlsanity.com/paper/2010.00747/) (2020)
- [MedCLIP: Contrastive Learning from Unpaired Medical Images and Text](https://mlsanity.com/paper/2210.10163/) (2022)
- [SLIP: Self-supervision meets Language-Image Pre-training](https://mlsanity.com/paper/2112.12750/) (2021)
- [Multi-Granularity Cross-modal Alignment for Generalized Medical Visual Representation Learning](https://mlsanity.com/paper/2210.06044/) (2022)
- [MedKLIP: Medical Knowledge Enhanced Language-Image Pre-Training in Radiology](https://mlsanity.com/paper/2301.02228/) (2023)
- [CXR-CLIP: Toward Large Scale Chest X-ray Language-Image Pre-training](https://mlsanity.com/paper/2310.13292/) (2023)
- [Mammo-CLIP: A Vision Language Foundation Model to Enhance Data Efficiency and Robustness in Mammography](https://mlsanity.com/paper/2405.12255/) (2024)
- [Act Like a Radiologist: Towards Reliable Multi-view Correspondence Reasoning for Mammogram Mass Detection](https://mlsanity.com/paper/2105.10160/) (2021)
- [Multi-view Local Co-occurrence and Global Consistency Learning Improve Mammogram Classification Generalisation](https://mlsanity.com/paper/2209.10478/) (2022)
- [Cross-view Relation Networks for Mammogram Mass Detection](https://mlsanity.com/paper/1907.00528/) (2019)
- [Mammo-CLIP: Leveraging Contrastive Language-Image Pre-training (CLIP) for Enhanced Breast Cancer Diagnosis with Multi-view Mammography](https://mlsanity.com/paper/2404.15946/) (2024)
- [Multi-View and Multi-Scale Alignment for Contrastive Language-Image Pre-training in Mammography](https://mlsanity.com/paper/2409.18119/) (2024)

## Built on by (most cited first, 1 of 1)

- [Benchmarking the Robustness of Foundation Models for Mammography under Domain Shift](https://mlsanity.com/paper/2607.10358/) (2026)

## Abstract (arXiv)

Mammography screening is an essential tool for early detection of breast cancer. The speed and accuracy of mammography interpretation have the potential to be improved with deep learning methods. However, the development of a foundation visual language model (VLM) is hindered by limited data and domain differences between natural and medical images. Existing mammography VLMs, adapted from natural images, often ignore domain-specific characteristics, such as multi-view relationships in mammography. Unlike radiologists who analyze both views together to process ipsilateral correspondence, current methods treat them as independent images or do not properly model the multi-view correspondence learning, losing critical geometric context and resulting in suboptimal prediction. We propose GLAM: Global and Local Alignment for Multi-view mammography for VLM pretraining using geometry guidance. By leveraging the prior knowledge about the multi-view imaging process of mammograms, our model learns local cross-view alignments and fine-grained local features through joint global and local, visual-visual, and visual-language contrastive learning. Pretrained on EMBED [14], one of the largest open mammography datasets, our model outperforms baselines across multiple datasets under different settings.