# Dual Interaction Network with Cross-Image Attention for Medical Image Segmentation

arXiv: https://arxiv.org/abs/2509.05953 · HTML: https://mlsanity.com/paper/2509.05953/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 36 of its 57 references that are in the map.
- First posted on arXiv 7 Sep 2025.

## Builds on (most cited first, 30 of 36)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [A ConvNet for the 2020s](https://mlsanity.com/paper/2201.03545/) (2022)
- [Gaussian Error Linear Units (GELUs)](https://mlsanity.com/paper/1606.08415/) (2016)
- [DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs](https://mlsanity.com/paper/1606.00915/) (2016)
- [SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformers](https://mlsanity.com/paper/2105.15203/) (2021)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [VMamba: Visual State Space Model](https://mlsanity.com/paper/2401.10166/) (2024)
- [CrossViT: Cross-Attention Multi-Scale Vision Transformer for Image Classification](https://mlsanity.com/paper/2103.14899/) (2021)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [PraNet: Parallel Reverse Attention Network for Polyp Segmentation](https://mlsanity.com/paper/2006.11392/) (2020)
- [UNet 3+: A Full-Scale Connected UNet for Medical Image Segmentation](https://mlsanity.com/paper/2004.08790/) (2020)
- [VM-UNet: Vision Mamba UNet for Medical Image Segmentation](https://mlsanity.com/paper/2402.02491/) (2024)
- [TransFuse: Fusing Transformers and CNNs for Medical Image Segmentation](https://mlsanity.com/paper/2102.08005/) (2021)
- [Learning to Enhance Low-Light Image via Zero-Reference Deep Curve Estimation](https://mlsanity.com/paper/2103.00860/) (2021)
- [Boundary loss for highly unbalanced segmentation](https://mlsanity.com/paper/1812.07032/) (2018)
- [UNeXt: MLP-based Rapid Medical Image Segmentation Network](https://mlsanity.com/paper/2203.04967/) (2022)
- [Polyp-PVT: Polyp Segmentation with Pyramid Vision Transformers](https://mlsanity.com/paper/2108.06932/) (2021)
- [Mixed Transformer U-Net For Medical Image Segmentation](https://mlsanity.com/paper/2111.04734/) (2021)
- [mmFormer: Multimodal Medical Transformer for Incomplete Multimodal Learning of Brain Tumor Segmentation](https://mlsanity.com/paper/2206.02425/) (2022)
- [HyperDense-Net: A hyper-densely connected CNN for multi-modal image segmentation](https://mlsanity.com/paper/1804.02967/) (2018)
- [EMCAD: Efficient Multi-scale Convolutional Attention Decoding for Medical Image Segmentation](https://mlsanity.com/paper/2405.06880/) (2024)
- [UACANet: Uncertainty Augmented Context Attention for Polyp Segmentation](https://mlsanity.com/paper/2107.02368/) (2021)
- [Stepwise Feature Fusion: Local Guides Global](https://mlsanity.com/paper/2203.03635/) (2022)
- [Modality-aware Mutual Learning for Multi-modal Medical Image Segmentation](https://mlsanity.com/paper/2107.09842/) (2021)
- [CaraNet: Context Axial Reverse Attention Network for Segmentation of Small Medical Objects](https://mlsanity.com/paper/2301.13366/) (2023)
- [NestedFormer: Nested Modality-Aware Transformer for Brain Tumor Segmentation](https://mlsanity.com/paper/2208.14876/) (2022)

## Built on by (most cited first, 1 of 1)

- [AdaKAN: A dual-branch adaptive Kolmogorov-Arnold network for medical image segmentation](https://mlsanity.com/paper/2607.22891/) (2026)

## Abstract (arXiv)

Medical image segmentation is a crucial method for assisting professionals in diagnosing various diseases through medical imaging. However, various factors such as noise, blurriness, and low contrast often hinder the accurate diagnosis of diseases. While numerous image enhancement techniques can mitigate these issues, they may also alter crucial information needed for accurate diagnosis in the original image. Conventional image fusion strategies, such as feature concatenation can address this challenge. However, they struggle to fully leverage the advantages of both original and enhanced images while suppressing the side effects of the enhancements. To overcome the problem, we propose a dual interactive fusion module (DIFM) that effectively exploits mutual complementary information from the original and enhanced images. DIFM employs cross-attention bidirectionally to simultaneously attend to corresponding spatial information across different images, subsequently refining the complementary features via global spatial attention. This interaction leverages low- to high-level features implicitly associated with diverse structural attributes like edges, blobs, and object shapes, resulting in enhanced features that embody important spatial characteristics. In addition, we introduce a multi-scale boundary loss based on gradient extraction to improve segmentation accuracy at object boundaries. Experimental results on the ACDC and Synapse datasets demonstrate the superiority of the proposed method quantitatively and qualitatively. Code available at: https://github.com/JJeong-Gari/DIN