# LGBP-OrgaNet: Learnable Gaussian Band Pass Fusion of CNN and Transformer Features for Robust Organoid Segmentation and Tracking

arXiv: https://arxiv.org/abs/2509.03221 · HTML: https://mlsanity.com/paper/2509.03221/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 31 references that are in the map.
- First posted on arXiv 3 Sep 2025.

## Builds on (most cited first, 9 of 9)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [CBAM: Convolutional Block Attention Module](https://mlsanity.com/paper/1807.06521/) (2018)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [UNet++: Redesigning Skip Connections to Exploit Multiscale Features in Image Segmentation](https://mlsanity.com/paper/1912.05074/) (2019)
- [Early Convolutions Help Transformers See Better](https://mlsanity.com/paper/2106.14881/) (2021)
- [HiFormer: Hierarchical Multi-scale Representations Using Transformers for Medical Image Segmentation](https://mlsanity.com/paper/2207.08518/) (2022)

## Abstract (arXiv)

Organoids replicate organ structure and function, playing a crucial role in fields such as tumor treatment and drug screening. Their shape and size can indicate their developmental status, but traditional fluorescence labeling methods risk compromising their structure. Therefore, this paper proposes an automated, non-destructive approach to organoid segmentation and tracking. We introduced the LGBP-OrgaNet, a deep learning-based system proficient in accurately segmenting, tracking, and quantifying organoids. The model leverages complementary information extracted from CNN and Transformer modules and introduces the innovative feature fusion module, Learnable Gaussian Band Pass Fusion, to merge data from two branches. Additionally, in the decoder, the model proposes a Bidirectional Cross Fusion Block to fuse multi-scale features, and finally completes the decoding through progressive concatenation and upsampling. SROrga demonstrates satisfactory segmentation accuracy and robustness on organoids segmentation datasets, providing a potent tool for organoid research.