# Multimodal Conditional MeshGAN for Personalized Aneurysm Growth Prediction

arXiv: https://arxiv.org/abs/2508.19862 · HTML: https://mlsanity.com/paper/2508.19862/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 15 of its 31 references that are in the map.
- First posted on arXiv 27 Aug 2025.

## Builds on (most cited first, 15 of 15)

- [Semi-Supervised Classification with Graph Convolutional Networks](https://mlsanity.com/paper/1609.02907/) (2016)
- [PointNet++: Deep Hierarchical Feature Learning on Point Sets in a Metric Space](https://mlsanity.com/paper/1706.02413/) (2017)
- [Fast Graph Representation Learning with PyTorch Geometric](https://mlsanity.com/paper/1903.02428/) (2019)
- [Geometric deep learning: going beyond Euclidean data](https://mlsanity.com/paper/1611.08097/) (2016)
- [Simple and Deep Graph Convolutional Networks](https://mlsanity.com/paper/2007.02133/) (2020)
- [Diffusion Probabilistic Models for 3D Point Cloud Generation](https://mlsanity.com/paper/2103.01458/) (2021)
- [TotalSegmentator: robust segmentation of 104 anatomical structures in CT images](https://mlsanity.com/paper/2208.05868/) (2022)
- [Generating 3D faces using Convolutional Mesh Autoencoders](https://mlsanity.com/paper/1807.10267/) (2018)
- [A Survey on Oversmoothing in Graph Neural Networks](https://mlsanity.com/paper/2303.10993/) (2023)
- [SpiralNet++: A Fast and Highly Efficient Mesh Convolution Operator](https://mlsanity.com/paper/1911.05856/) (2019)
- [Scattering GCN: Overcoming Oversmoothness in Graph Convolutional Networks](https://mlsanity.com/paper/2003.08414/) (2020)
- [Graph Neural Networks are Inherently Good Generalizers: Insights by Bridging GNNs and MLPs](https://mlsanity.com/paper/2212.09034/) (2022)
- [FaceTuneGAN: Face Autoencoder for Convolutional Expression Transfer Using Neural Generative Adversarial Networks](https://mlsanity.com/paper/2112.00532/) (2021)
- [PU-MFA : Point Cloud Up-sampling via Multi-scale Features Attention](https://mlsanity.com/paper/2208.10968/) (2022)
- [Computer-aided shape features extraction and regression models for predicting the ascending aortic aneurysm growth rate](https://mlsanity.com/paper/2503.02915/) (2025)

## Abstract (arXiv)

Personalized, accurate prediction of aortic aneurysm progression is essential for timely intervention but remains challenging due to the need to model both subtle local deformations and global anatomical changes within complex 3D geometries. We propose MCMeshGAN, the first multimodal conditional mesh-to-mesh generative adversarial network for 3D aneurysm growth prediction. MCMeshGAN introduces a dual-branch architecture combining a novel local KNN-based convolutional network (KCN) to preserve fine-grained geometric details and a global graph convolutional network (GCN) to capture long-range structural context, overcoming the over-smoothing limitations of deep GCNs. A dedicated condition branch encodes clinical attributes (age, sex) and the target time interval to generate anatomically plausible, temporally controlled predictions, enabling retrospective and prospective modeling. We curated TAAMesh, a new longitudinal thoracic aortic aneurysm mesh dataset consisting of 590 multimodal records (CT scans, 3D meshes, and clinical data) from 208 patients. Extensive experiments demonstrate that MCMeshGAN consistently outperforms state-of-the-art baselines in both geometric accuracy and clinically important diameter estimation. This framework offers a robust step toward clinically deployable, personalized 3D disease trajectory modeling. The source code for MCMeshGAN and the baseline methods is publicly available at https://github.com/ImperialCollegeLondon/MCMeshGAN.