# ControlEchoSynth: Boosting Ejection Fraction Estimation Models via Controlled Video Diffusion

arXiv: https://arxiv.org/abs/2508.17631 · HTML: https://mlsanity.com/paper/2508.17631/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 21 of its 33 references that are in the map.
- First posted on arXiv 25 Aug 2025.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 21 of 21)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Hierarchical Text-Conditional Image Generation with CLIP Latents](https://mlsanity.com/paper/2204.06125/) (2022)
- [Adding Conditional Control to Text-to-Image Diffusion Models](https://mlsanity.com/paper/2302.05543/) (2023)
- [Stable Video Diffusion: Scaling Latent Video Diffusion Models to Large Datasets](https://mlsanity.com/paper/2311.15127/) (2023)
- [Video Diffusion Models](https://mlsanity.com/paper/2204.03458/) (2022)
- [SDEdit: Guided Image Synthesis and Editing with Stochastic Differential Equations](https://mlsanity.com/paper/2108.01073/) (2021)
- [Imagen Video: High Definition Video Generation with Diffusion Models](https://mlsanity.com/paper/2210.02303/) (2022)
- [Make-A-Video: Text-to-Video Generation without Text-Video Data](https://mlsanity.com/paper/2209.14792/) (2022)
- [AnimateDiff: Animate Your Personalized Text-to-Image Diffusion Models without Specific Tuning](https://mlsanity.com/paper/2307.04725/) (2023)
- [Cascaded Diffusion Models for High Fidelity Image Generation](https://mlsanity.com/paper/2106.15282/) (2021)
- [A Closer Look at Spatiotemporal Convolutions for Action Recognition](https://mlsanity.com/paper/1711.11248/) (2017)
- [Deep Learning for Segmentation using an Open Large-Scale Dataset in 2D Echocardiography](https://mlsanity.com/paper/1908.06948/) (2019)
- [UniFormer: Unified Transformer for Efficient Spatiotemporal Representation Learning](https://mlsanity.com/paper/2201.04676/) (2022)
- [EchoGNN: Explainable Ejection Fraction Estimation with Graph Neural Networks](https://mlsanity.com/paper/2208.14003/) (2022)
- [EchoCoTr: Estimation of the Left Ventricular Ejection Fraction from Spatiotemporal Echocardiography](https://mlsanity.com/paper/2209.04242/) (2022)
- [Light-weight spatio-temporal graphs for segmentation and ejection fraction prediction in cardiac ultrasound](https://mlsanity.com/paper/2207.02549/) (2022)
- [Echocardiography video synthesis from end diastolic semantic map via diffusion model](https://mlsanity.com/paper/2310.07131/) (2023)

## Built on by (most cited first, 1 of 1)

- [EchoLVFM: One-Step Video Generation via Latent Flow Matching for Echocardiogram Synthesis](https://mlsanity.com/paper/2603.13967/) (2026)

## Abstract (arXiv)

Synthetic data generation represents a significant advancement in boosting the performance of machine learning (ML) models, particularly in fields where data acquisition is challenging, such as echocardiography. The acquisition and labeling of echocardiograms (echo) for heart assessment, crucial in point-of-care ultrasound (POCUS) settings, often encounter limitations due to the restricted number of echo views available, typically captured by operators with varying levels of experience. This study proposes a novel approach for enhancing clinical diagnosis accuracy by synthetically generating echo views. These views are conditioned on existing, real views of the heart, focusing specifically on the estimation of ejection fraction (EF), a critical parameter traditionally measured from biplane apical views. By integrating a conditional generative model, we demonstrate an improvement in EF estimation accuracy, providing a comparative analysis with traditional methods. Preliminary results indicate that our synthetic echoes, when used to augment existing datasets, not only enhance EF estimation but also show potential in advancing the development of more robust, accurate, and clinically relevant ML models. This approach is anticipated to catalyze further research in synthetic data applications, paving the way for innovative solutions in medical imaging diagnostics.