# One VLM, Two Roles: Stage-Wise Routing and Specialty-Level Deployment for Clinical Workflows

arXiv: https://arxiv.org/abs/2508.16839 · HTML: https://mlsanity.com/paper/2508.16839/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 16 of its 44 references that are in the map.
- First posted on arXiv 22 Aug 2025.

## Builds on (most cited first, 16 of 16)

- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Qwen2-VL: Enhancing Vision-Language Model's Perception of the World at Any Resolution](https://mlsanity.com/paper/2409.12191/) (2024)
- [QLoRA: Efficient Finetuning of Quantized LLMs](https://mlsanity.com/paper/2305.14314/) (2023)
- [Learning without Forgetting](https://mlsanity.com/paper/1606.09282/) (2016)
- [HuggingGPT: Solving AI Tasks with ChatGPT and its Friends in Hugging Face](https://mlsanity.com/paper/2303.17580/) (2023)
- [SparseGPT: Massive Language Models Can Be Accurately Pruned in One-Shot](https://mlsanity.com/paper/2301.00774/) (2023)
- [Model Cards for Model Reporting](https://mlsanity.com/paper/1810.03993/) (2018)
- [ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseases](https://mlsanity.com/paper/1705.02315/) (2017)
- [Contrastive Learning of Medical Visual Representations from Paired Images and Text](https://mlsanity.com/paper/2010.00747/) (2020)
- [The Liver Tumor Segmentation Benchmark (LiTS)](https://mlsanity.com/paper/1901.04056/) (2019)
- [MedGemma Technical Report](https://mlsanity.com/paper/2507.05201/) (2025)
- [SelectiveNet: A Deep Neural Network with an Integrated Reject Option](https://mlsanity.com/paper/1901.09192/) (2019)
- [Colonoscopy Polyp Detection and Classification: Dataset Creation and Comparative Evaluations](https://mlsanity.com/paper/2104.10824/) (2021)
- [DeepLesion: Automated Deep Mining, Categorization and Detection of Significant Radiology Image Findings using Large-Scale Clinical Lesion Annotations](https://mlsanity.com/paper/1710.01766/) (2017)
- [UMIT: Unifying Medical Imaging Tasks via Vision-Language Models](https://mlsanity.com/paper/2503.15892/) (2025)
- [Agentic AI framework for End-to-End Medical Data Inference](https://mlsanity.com/paper/2507.18115/) (2025)

## Built on by (most cited first, 3 of 3)

- [From Wearables to Warnings: Predicting Pain Spikes in Patients with Opioid Use Disorder](https://mlsanity.com/paper/2511.19577/) (2025)
- [Tracing the Heart: An Evidence-Linked Pipeline for Heart-Failure Feature Engineering](https://mlsanity.com/paper/2608.06366/) (2026)
- [Reliability Stress Tests and Decision-Time Routing for Chest X-ray Vision-Language Models](https://mlsanity.com/paper/2610.02270/) (2026)

## Abstract (arXiv)

Clinical ML workflows are often fragmented and inefficient: triage, task selection, and model deployment are handled by a patchwork of task-specific networks. These pipelines are rarely aligned with data-science practice, reducing efficiency and increasing operational cost. They also lack data-driven model identification (from imaging/tabular inputs) and standardized delivery of model outputs. We present a framework that employs a single vision-language model (VLM) in two complementary, modular roles. First (Solution 1): the VLM acts as an aware model-card matcher that routes an incoming image to the appropriate specialist model via a three-stage workflow (modality -> primary abnormality -> model-card ID). Reliability is improved by (i) stage-wise prompts enabling early termination via "None"/"Other" and (ii) a calibrated top-2 answer selector with a stage-wise cutoff. This raises routing accuracy by +9 and +11 percentage points on the training and held-out splits, respectively, compared with a baseline router, and improves held-out calibration (lower Expected Calibration Error, ECE). Second (Solution 2): we fine-tune the same VLM on specialty-specific datasets so that one model per specialty covers multiple downstream tasks, simplifying deployment while maintaining performance. Across gastroenterology, hematology, ophthalmology, pathology, and radiology, this single-model deployment matches or approaches specialized baselines. Together, these solutions reduce data-science effort through more accurate selection, simplify monitoring and maintenance by consolidating task-specific models, and increase transparency via per-stage justifications and calibrated thresholds. Each solution stands alone, and in combination they offer a practical, modular path from triage to deployment.
