# LLM-Based Agents for Competitive Landscape Mapping in Drug Asset Due Diligence

arXiv: https://arxiv.org/abs/2508.16571 · HTML: https://mlsanity.com/paper/2508.16571/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use.
- Builds on 8 of its 19 references that are in the map.
- First posted on arXiv 22 Aug 2025.

## Placed in

- LLM agents and tool use / [Medical and scientific domain agents](https://mlsanity.com/agents/medical-and-scientific-domain-agents/)

## Builds on (most cited first, 8 of 8)

- [WebArena: A Realistic Web Environment for Building Autonomous Agents](https://mlsanity.com/paper/2307.13854/) (2023)
- [Mind2Web: Towards a Generalist Agent for the Web](https://mlsanity.com/paper/2306.06070/) (2023)
- [BrowseComp: A Simple Yet Challenging Benchmark for Browsing Agents](https://mlsanity.com/paper/2504.12516/) (2025)
- [PaperBench: Evaluating AI's Ability to Replicate AI Research](https://mlsanity.com/paper/2504.01848/) (2025)
- [WebLINX: Real-World Website Navigation with Multi-Turn Dialogue](https://mlsanity.com/paper/2402.05930/) (2024)
- [Benchmarking large language models for biomedical natural language processing applications and recommendations](https://mlsanity.com/paper/2305.16326/) (2023)
- [Hopping Too Late: Exploring the Limitations of Large Language Models on Multi-Hop Queries](https://mlsanity.com/paper/2406.12775/) (2024)
- [Inverse Scaling in Test-Time Compute](https://mlsanity.com/paper/2507.14417/) (2025)

## Built on by (most cited first, 2 of 2)

- [LLM Agents in Law: Taxonomy, Applications, and Challenges](https://mlsanity.com/paper/2601.06216/) (2026)
- [Hunt Globally: Wide Search AI Agents for Drug Asset Scouting in Investing, Business Development, and Competitive Intelligence](https://mlsanity.com/paper/2602.15019/) (2026)

## Abstract (arXiv)

In this paper, we describe and benchmark a competitor-discovery component used within an agentic AI system for fast drug asset due diligence. A competitor-discovery AI agent, given an indication, retrieves all drugs comprising the competitive landscape of that indication and extracts canonical attributes for these drugs. The competitor definition is investor-specific, and data is paywalled/licensed, fragmented across registries, ontology-mismatched by indication, alias-heavy for drug names, multimodal, and rapidly changing. Although considered the best tool for this problem, the current LLM-based AI systems aren't capable of reliably retrieving all competing drug names, and there is no accepted public benchmark for this task. To address the lack of evaluation, we use LLM-based agents to transform five years of multi-modal, unstructured diligence memos from a private biotech VC fund into a structured evaluation corpus mapping indications to competitor drugs with normalized attributes. We also introduce a competitor validating LLM-as-a-judge agent that filters out false positives from the list of predicted competitors to maximize precision and suppress hallucinations. On this benchmark, our competitor-discovery agent achieves 83% recall, exceeding OpenAI Deep Research (65%) and Perplexity Labs (60%). The system is deployed in production with enterprise users; in a case study with a biotech VC investment fund, analyst turnaround time dropped from 2.5 days to ~3 hours (~20x) for the competitive analysis.
