# Transfer learning optimization based on evolutionary selective fine tuning

arXiv: https://arxiv.org/abs/2508.15367 · HTML: https://mlsanity.com/paper/2508.15367/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 10 of its 26 references that are in the map.
- First posted on arXiv 21 Aug 2025.

## Builds on (most cited first, 10 of 10)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Describing Textures in the Wild](https://mlsanity.com/paper/1311.3618/) (2013)
- [Fine-Grained Visual Classification of Aircraft](https://mlsanity.com/paper/1306.5151/) (2013)
- [Fine-Tuning can Distort Pretrained Features and Underperform Out-of-Distribution](https://mlsanity.com/paper/2202.10054/) (2022)
- [Explicit Inductive Bias for Transfer Learning with Convolutional Networks](https://mlsanity.com/paper/1802.01483/) (2018)
- [Surgical Fine-Tuning Improves Adaptation to Distribution Shifts](https://mlsanity.com/paper/2210.11466/) (2022)
- [A Patient-Centric Dataset of Images and Metadata for Identifying Melanomas Using Clinical Context](https://mlsanity.com/paper/2008.07360/) (2020)
- [Comparison of fine-tuning strategies for transfer learning in medical image classification](https://mlsanity.com/paper/2406.10050/) (2024)
- [Fine-Tuning Pretrained Language Models With Label Attention for Biomedical Text Classification](https://mlsanity.com/paper/2108.11809/) (2021)

## Abstract (arXiv)

Deep learning has shown substantial progress in image analysis. However, the computational demands of large, fully trained models remain a consideration. Transfer learning offers a strategy for adapting pre-trained models to new tasks. Traditional fine-tuning often involves updating all model parameters, which can potentially lead to overfitting and higher computational costs. This paper introduces BioTune, an evolutionary adaptive fine-tuning technique that selectively fine-tunes layers to enhance transfer learning efficiency. BioTune employs an evolutionary algorithm to identify a focused set of layers for fine-tuning, aiming to optimize model performance on a given target task. Evaluation across nine image classification datasets from various domains indicates that BioTune achieves competitive or improved accuracy and efficiency compared to existing fine-tuning methods such as AutoRGN and LoRA. By concentrating the fine-tuning process on a subset of relevant layers, BioTune reduces the number of trainable parameters, potentially leading to decreased computational cost and facilitating more efficient transfer learning across diverse data characteristics and distributions.