# Cross-view Generalized Diffusion Model for Sparse-view CT Reconstruction

arXiv: https://arxiv.org/abs/2508.10313 · HTML: https://mlsanity.com/paper/2508.10313/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 18 of its 30 references that are in the map.
- First posted on arXiv 14 Aug 2025.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 18 of 18)

- [Diffusion Posterior Sampling for General Noisy Inverse Problems](https://mlsanity.com/paper/2209.14687/) (2022)
- [Improving Diffusion Models for Inverse Problems using Manifold Constraints](https://mlsanity.com/paper/2206.00941/) (2022)
- [Deep Convolutional Neural Network for Inverse Problems in Imaging](https://mlsanity.com/paper/1611.03679/) (2016)
- [Cold Diffusion: Inverting Arbitrary Image Transforms Without Noise](https://mlsanity.com/paper/2208.09392/) (2022)
- [DuDoNet: Dual Domain Network for CT Metal Artifact Reduction](https://mlsanity.com/paper/1907.00273/) (2019)
- [Direct Diffusion Bridge using Data Consistency for Inverse Problems](https://mlsanity.com/paper/2305.19809/) (2023)
- [Deep-neural-network based sinogram synthesis for sparse-view CT image reconstruction](https://mlsanity.com/paper/1803.00694/) (2018)
- [TorchRadon: Fast Differentiable Routines for Computed Tomography](https://mlsanity.com/paper/2009.14788/) (2020)
- [Learning Deep Intensity Field for Extremely Sparse-View CBCT Reconstruction](https://mlsanity.com/paper/2303.06681/) (2023)
- [FreeSeed: Frequency-band-aware and Self-guided Network for Sparse-view CT Reconstruction](https://mlsanity.com/paper/2307.05890/) (2023)
- [Stage-by-stage Wavelet Optimization Refinement Diffusion Model for Sparse-View CT Reconstruction](https://mlsanity.com/paper/2308.15942/) (2023)
- [Learning 3D Gaussians for Extremely Sparse-View Cone-Beam CT Reconstruction](https://mlsanity.com/paper/2407.01090/) (2024)
- [C^2RV: Cross-Regional and Cross-View Learning for Sparse-View CBCT Reconstruction](https://mlsanity.com/paper/2406.03902/) (2024)
- [Learning to Distill Global Representation for Sparse-View CT](https://mlsanity.com/paper/2308.08463/) (2023)
- [CoSIGN: Few-Step Guidance of ConSIstency Model to Solve General INverse Problems](https://mlsanity.com/paper/2407.12676/) (2024)
- [Sinogram interpolation for sparse-view micro-CT with deep learning neural network](https://mlsanity.com/paper/1902.03362/) (2019)
- [DeepSparse: A Foundation Model for Sparse-View CBCT Reconstruction](https://mlsanity.com/paper/2505.02628/) (2025)
- [Spatial-Division Augmented Occupancy Field for Bone Shape Reconstruction from Biplanar X-Rays](https://mlsanity.com/paper/2407.15433/) (2024)

## Built on by (most cited first, 6 of 6)

- [Resolution-Agnostic Neural Operators for Multi-Rate Sparse-View CT](https://mlsanity.com/paper/2512.12236/) (2025)
- [Efficient Flow Matching for Sparse-View CT Reconstruction](https://mlsanity.com/paper/2603.00205/) (2026)
- [ReCo-Diff: Residual-Conditioned Deterministic Sampling for Cold Diffusion in Sparse-View CT](https://mlsanity.com/paper/2603.02691/) (2026)
- [SONAR: A Structure-Consistent Neural Operator for Null-Space-Aware Sparse View CT Reconstruction](https://mlsanity.com/paper/2609.13688/) (2026)
- [Dose-Aware Cold Diffusion with Physics Consistency for Generalizable Low-Dose CT Reconstruction](https://mlsanity.com/paper/2609.18943/) (2026)
- [RePrior: Measurement-Reconciled Prior Correction for Sparse-View CBCT Reconstruction](https://mlsanity.com/paper/2610.14102/) (2026)

## Abstract (arXiv)

Sparse-view computed tomography (CT) reduces radiation exposure by subsampling projection views, but conventional reconstruction methods produce severe streak artifacts with undersampled data. While deep-learning-based methods enable single-step artifact suppression, they often produce over-smoothed results under significant sparsity. Though diffusion models improve reconstruction via iterative refinement and generative priors, they require hundreds of sampling steps and struggle with stability in highly sparse regimes. To tackle these concerns, we present the Cross-view Generalized Diffusion Model (CvG-Diff), which reformulates sparse-view CT reconstruction as a generalized diffusion process. Unlike existing diffusion approaches that rely on stochastic Gaussian degradation, CvG-Diff explicitly models image-domain artifacts caused by angular subsampling as a deterministic degradation operator, leveraging correlations across sparse-view CT at different sample rates. To address the inherent artifact propagation and inefficiency of sequential sampling in generalized diffusion model, we introduce two innovations: Error-Propagating Composite Training (EPCT), which facilitates identifying error-prone regions and suppresses propagated artifacts, and Semantic-Prioritized Dual-Phase Sampling (SPDPS), an adaptive strategy that prioritizes semantic correctness before detail refinement. Together, these innovations enable CvG-Diff to achieve high-quality reconstructions with minimal iterations, achieving 38.34 dB PSNR and 0.9518 SSIM for 18-view CT using only 10 steps on AAPM-LDCT dataset. Extensive experiments demonstrate the superiority of CvG-Diff over state-of-the-art sparse-view CT reconstruction methods. The code is available at https://github.com/xmed-lab/CvG-Diff.
