# Prototype-Guided Diffusion: Visual Conditioning without External Memory

arXiv: https://arxiv.org/abs/2508.09922 · HTML: https://mlsanity.com/paper/2508.09922/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Diffusion foundations and sampling, one of 14 directions in Diffusion models.
- Builds on 23 of its 28 references that are in the map.
- First posted on arXiv 13 Aug 2025.

## Placed in

- Diffusion models / [Diffusion foundations and sampling](https://mlsanity.com/diffusion/diffusion-foundations-and-sampling/)

## Builds on (most cited first, 23 of 23)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [Deep Unsupervised Learning using Nonequilibrium Thermodynamics](https://mlsanity.com/paper/1503.03585/) (2015)
- [Photorealistic Text-to-Image Diffusion Models with Deep Language Understanding](https://mlsanity.com/paper/2205.11487/) (2022)
- [Classifier-Free Diffusion Guidance](https://mlsanity.com/paper/2207.12598/) (2022)
- [SDXL: Improving Latent Diffusion Models for High-Resolution Image Synthesis](https://mlsanity.com/paper/2307.01952/) (2023)
- [Taming Transformers for High-Resolution Image Synthesis](https://mlsanity.com/paper/2012.09841/) (2020)
- [Prototypical Networks for Few-shot Learning](https://mlsanity.com/paper/1703.05175/) (2017)
- [Improved Techniques for Training GANs](https://mlsanity.com/paper/1606.03498/) (2016)
- [Consistency Models](https://mlsanity.com/paper/2303.01469/) (2023)
- [EuroSAT: A Novel Dataset and Deep Learning Benchmark for Land Use and Land Cover Classification](https://mlsanity.com/paper/1709.00029/) (2017)
- [RePaint: Inpainting using Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2201.09865/) (2022)
- [Demystifying MMD GANs](https://mlsanity.com/paper/1801.01401/) (2018)
- [REVEAL: Retrieval-Augmented Visual-Language Pre-Training with Multi-Source Multimodal Knowledge Memory](https://mlsanity.com/paper/2212.05221/) (2022)
- [Diffusion Models Beat GANs on Topology Optimization](https://mlsanity.com/paper/2208.09591/) (2022)
- [Shifted Diffusion for Text-to-image Generation](https://mlsanity.com/paper/2211.15388/) (2022)
- [ProtoDiff: Learning to Learn Prototypical Networks by Task-Guided Diffusion](https://mlsanity.com/paper/2306.14770/) (2023)
- [ProtoDiffusion: Classifier-Free Diffusion Guidance with Prototype Learning](https://mlsanity.com/paper/2307.01924/) (2023)
- [Class-Prototype Conditional Diffusion Model with Gradient Projection for Continual Learning](https://mlsanity.com/paper/2312.06710/) (2023)

## Abstract (arXiv)

Diffusion models achieve state-of-the-art image generation but remain computationally costly due to iterative denoising. Latent-space models like Stable Diffusion reduce overhead yet lose fine detail, while retrieval-augmented methods improve efficiency but rely on large memory banks, static similarity models, and rigid infrastructures. We introduce the Prototype Diffusion Model (PDM), which embeds prototype learning into the diffusion process to provide adaptive, memory-free conditioning. Instead of retrieving references, PDM learns compact visual prototypes from clean features via contrastive learning, then aligns noisy representations with semantically relevant patterns during denoising. Experiments demonstrate that PDM sustains high generation quality while lowering computational and storage costs, offering a scalable alternative to retrieval-based conditioning.