# Dynamic Survival Prediction using Longitudinal Images based on Transformer

arXiv: https://arxiv.org/abs/2508.09328 · HTML: https://mlsanity.com/paper/2508.09328/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 15 of its 53 references that are in the map.
- First posted on arXiv 12 Aug 2025.

## Builds on (most cited first, 15 of 15)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Visualizing and Understanding Convolutional Networks](https://mlsanity.com/paper/1311.2901/) (2013)
- [A Survey on Deep Learning in Medical Image Analysis](https://mlsanity.com/paper/1702.05747/) (2017)
- [DeepSurv: Personalized Treatment Recommender System Using A Cox Proportional Hazards Deep Neural Network](https://mlsanity.com/paper/1606.00931/) (2016)
- [Spatial-Temporal Transformer Networks for Traffic Flow Forecasting](https://mlsanity.com/paper/2001.02908/) (2020)
- [Time-to-Event Prediction with Neural Networks and Cox Regression](https://mlsanity.com/paper/1907.00825/) (2019)
- [Machine Learning for Survival Analysis: A Survey](https://mlsanity.com/paper/1708.04649/) (2017)
- [Transformer-based Spatial-Temporal Feature Learning for EEG Decoding](https://mlsanity.com/paper/2106.11170/) (2021)
- [Deep Learning for Survival Analysis: A Review](https://mlsanity.com/paper/2305.14961/) (2023)
- [Deep Survival Analysis](https://mlsanity.com/paper/1608.02158/) (2016)
- [Deep Recurrent Survival Analysis](https://mlsanity.com/paper/1809.02403/) (2018)
- [Deep Learning for Patient-Specific Kidney Graft Survival Analysis](https://mlsanity.com/paper/1705.10245/) (2017)
- [Deep survival analysis with longitudinal X-rays for COVID-19](https://mlsanity.com/paper/2108.09641/) (2021)

## Built on by (most cited first, 1 of 1)

- [PRISM: A Framework Harnessing Unsupervised Visual Representations and Textual Prompts for Explainable MACE Survival Prediction from Cardiac Cine MRI](https://mlsanity.com/paper/2508.19325/) (2025)

## Abstract (arXiv)

Survival analysis utilizing multiple longitudinal medical images plays a pivotal role in the early detection and prognosis of diseases by providing insight beyond single-image evaluations. However, current methodologies often inadequately utilize censored data, overlook correlations among longitudinal images measured over multiple time points, and lack interpretability. We introduce SurLonFormer, a novel Transformer-based neural network that integrates longitudinal medical imaging with structured data for survival prediction. Our architecture comprises three key components: a Vision Encoder for extracting spatial features, a Sequence Encoder for aggregating temporal information, and a Survival Encoder based on the Cox proportional hazards model. This framework effectively incorporates censored data, addresses scalability issues, and enhances interpretability through occlusion sensitivity analysis and dynamic survival prediction. Extensive simulations and a real-world application in Alzheimer's disease analysis demonstrate that SurLonFormer achieves superior predictive performance and successfully identifies disease-related imaging biomarkers.
