# Automatic and standardized surgical reporting for central nervous system tumors

arXiv: https://arxiv.org/abs/2508.08916 · HTML: https://mlsanity.com/paper/2508.08916/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 13 of its 36 references that are in the map.
- First posted on arXiv 12 Aug 2025.

## Builds on (most cited first, 13 of 13)

- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Images](https://mlsanity.com/paper/2201.01266/) (2022)
- [MONAI: An open-source framework for deep learning in healthcare](https://mlsanity.com/paper/2211.02701/) (2022)
- [MedPerf: Open Benchmarking Platform for Medical Artificial Intelligence using Federated Evaluation](https://mlsanity.com/paper/2110.01406/) (2021)
- [The 2024 Brain Tumor Segmentation (BraTS) Challenge: Glioma Segmentation on Post-treatment MRI](https://mlsanity.com/paper/2405.18368/) (2024)
- [The Brain Tumor Segmentation (BraTS-METS) Challenge 2023: Brain Metastasis Segmentation on Pre-treatment MRI](https://mlsanity.com/paper/2306.00838/) (2023)
- [How we won BraTS 2023 Adult Glioma challenge? Just faking it! Enhanced Synthetic Data Augmentation and Model Ensemble for brain tumour segmentation](https://mlsanity.com/paper/2402.17317/) (2024)
- [Preoperative brain tumor imaging: models and software for segmentation and standardized reporting](https://mlsanity.com/paper/2204.14199/) (2022)
- [A self-supervised learning strategy for postoperative brain cavity segmentation simulating resections](https://mlsanity.com/paper/2105.11239/) (2021)
- [Segmentation of glioblastomas in early post-operative multi-modal MRI with deep neural networks](https://mlsanity.com/paper/2304.08881/) (2023)
- [Raidionics: an open software for pre- and postoperative central nervous system tumor segmentation and standardized reporting](https://mlsanity.com/paper/2305.14351/) (2023)
- [Comparison of different automatic solutions for resection cavity segmentation in postoperative MRI volumes including longitudinal acquisitions](https://mlsanity.com/paper/2210.07806/) (2022)

## Abstract (arXiv)

Magnetic resonance (MR) imaging is essential for evaluating central nervous system (CNS) tumors, guiding surgical planning, treatment decisions, and assessing postoperative outcomes and complication risks. While recent work has advanced automated tumor segmentation and report generation, most efforts have focused on preoperative data, with limited attention to postoperative imaging analysis. This study introduces a comprehensive pipeline for standardized postsurtical reporting in CNS tumors. Using the Attention U-Net architecture, segmentation models were trained for the preoperative (non-enhancing) tumor core, postoperative contrast-enhancing residual tumor, and resection cavity. Additionally, MR sequence classification and tumor type identification for contrast-enhancing lesions were explored using the DenseNet architecture. The models were integrated into a reporting pipeline, following the RANO 2.0 guidelines. Training was conducted on multicentric datasets comprising 2000 to 7000 patients, using a 5-fold cross-validation. Evaluation included patient-, voxel-, and object-wise metrics, with benchmarking against the latest BraTS challenge results. The segmentation models achieved average voxel-wise Dice scores of 87%, 66%, 70%, and 77% for the tumor core, non-enhancing tumor core, contrast-enhancing residual tumor, and resection cavity, respectively. Classification models reached 99.5% balanced accuracy in MR sequence classification and 80% in tumor type classification. The pipeline presented in this study enables robust, automated segmentation, MR sequence classification, and standardized report generation aligned with RANO 2.0 guidelines, enhancing postoperative evaluation and clinical decision-making. The proposed models and methods were integrated into Raidionics, open-source software platform for CNS tumor analysis, now including a dedicated module for postsurgical analysis.
