# MultiMedEdit: A Scenario-Aware Benchmark for Evaluating Knowledge Editing in Medical VQA

arXiv: https://arxiv.org/abs/2508.07022 · HTML: https://mlsanity.com/paper/2508.07022/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 29 of its 43 references that are in the map.
- First posted on arXiv 9 Aug 2025.

## Builds on (most cited first, 29 of 29)

- [Locating and Editing Factual Associations in GPT](https://mlsanity.com/paper/2202.05262/) (2022)
- [VQA: Visual Question Answering](https://mlsanity.com/paper/1505.00468/) (2015)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [Mass-Editing Memory in a Transformer](https://mlsanity.com/paper/2210.07229/) (2022)
- [PaLI: A Jointly-Scaled Multilingual Language-Image Model](https://mlsanity.com/paper/2209.06794/) (2022)
- [The Dawn of LMMs: Preliminary Explorations with GPT-4V(ision)](https://mlsanity.com/paper/2309.17421/) (2023)
- [An Empirical Study of Catastrophic Forgetting in Large Language Models During Continual Fine-tuning](https://mlsanity.com/paper/2308.08747/) (2023)
- [Fast Model Editing at Scale](https://mlsanity.com/paper/2110.11309/) (2021)
- [Memory-Based Model Editing at Scale](https://mlsanity.com/paper/2206.06520/) (2022)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [Editing Large Language Models: Problems, Methods, and Opportunities](https://mlsanity.com/paper/2305.13172/) (2023)
- [Can We Edit Factual Knowledge by In-Context Learning?](https://mlsanity.com/paper/2305.12740/) (2023)
- [Aging with GRACE: Lifelong Model Editing with Discrete Key-Value Adaptors](https://mlsanity.com/paper/2211.11031/) (2022)
- [AlphaEdit: Null-Space Constrained Knowledge Editing for Language Models](https://mlsanity.com/paper/2410.02355/) (2024)
- [MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understanding](https://mlsanity.com/paper/2501.18362/) (2025)
- [HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scale](https://mlsanity.com/paper/2406.19280/) (2024)
- [OmniMedVQA: A New Large-Scale Comprehensive Evaluation Benchmark for Medical LVLM](https://mlsanity.com/paper/2402.09181/) (2024)
- [Revisiting Catastrophic Forgetting in Large Language Model Tuning](https://mlsanity.com/paper/2406.04836/) (2024)
- [Medical Hallucinations in Foundation Models and Their Impact on Healthcare](https://mlsanity.com/paper/2503.05777/) (2025)
- [Learning to Edit: Aligning LLMs with Knowledge Editing](https://mlsanity.com/paper/2402.11905/) (2024)
- [Lifelong Knowledge Editing for LLMs with Retrieval-Augmented Continuous Prompt Learning](https://mlsanity.com/paper/2405.03279/) (2024)
- [MedFrameQA: A Multi-Image Medical VQA Benchmark for Clinical Reasoning](https://mlsanity.com/paper/2505.16964/) (2025)
- [MediConfusion: Can you trust your AI radiologist? Probing the reliability of multimodal medical foundation models](https://mlsanity.com/paper/2409.15477/) (2024)
- [Retrieval-enhanced Knowledge Editing in Language Models for Multi-Hop Question Answering](https://mlsanity.com/paper/2403.19631/) (2024)
- [Worse than Random? An Embarrassingly Simple Probing Evaluation of Large Multimodal Models in Medical VQA](https://mlsanity.com/paper/2405.20421/) (2024)
- [CaKE: Circuit-aware Editing Enables Generalizable Knowledge Learners](https://mlsanity.com/paper/2503.16356/) (2025)
- [O-Edit: Orthogonal Subspace Editing for Language Model Sequential Editing](https://mlsanity.com/paper/2410.11469/) (2024)
- [Tracing and Reversing Edits in LLMs](https://mlsanity.com/paper/2505.20819/) (2025)
- [MindBridge: Scalable and Cross-Model Knowledge Editing via Memory-Augmented Modality](https://mlsanity.com/paper/2503.02701/) (2025)

## Abstract (arXiv)

Knowledge editing (KE) provides a scalable approach for updating factual knowledge in large language models without full retraining. While previous studies have demonstrated effectiveness in general domains and medical QA tasks, little attention has been paid to KE in multimodal medical scenarios. Unlike text-only settings, medical KE demands integrating updated knowledge with visual reasoning to support safe and interpretable clinical decisions. To address this gap, we propose MultiMedEdit, the first benchmark tailored to evaluating KE in clinical multimodal tasks. Our framework spans both understanding and reasoning task types, defines a three-dimensional metric suite (reliability, generality, and locality), and supports cross-paradigm comparisons across general and domain-specific models. We conduct extensive experiments under single-editing and lifelong-editing settings. Results suggest that current methods struggle with generalization and long-tail reasoning, particularly in complex clinical workflows. We further present an efficiency analysis (e.g., edit latency, memory footprint), revealing practical trade-offs in real-world deployment across KE paradigms. Overall, MultiMedEdit not only reveals the limitations of current approaches but also provides a solid foundation for developing clinically robust knowledge editing techniques in the future.