# Frequency Prior Guided Matching: A Data Augmentation Approach for Generalizable Semi-Supervised Polyp Segmentation

arXiv: https://arxiv.org/abs/2508.06517 · HTML: https://mlsanity.com/paper/2508.06517/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 33 of its 58 references that are in the map.
- First posted on arXiv 30 Jul 2025.

## Builds on (most cited first, 30 of 33)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [mixup: Beyond Empirical Risk Minimization](https://mlsanity.com/paper/1710.09412/) (2017)
- [CutMix: Regularization Strategy to Train Strong Classifiers with Localizable Features](https://mlsanity.com/paper/1905.04899/) (2019)
- [FixMatch: Simplifying Semi-Supervised Learning with Consistency and Confidence](https://mlsanity.com/paper/2001.07685/) (2020)
- [Improved Regularization of Convolutional Neural Networks with Cutout](https://mlsanity.com/paper/1708.04552/) (2017)
- [AugMix: A Simple Data Processing Method to Improve Robustness and Uncertainty](https://mlsanity.com/paper/1912.02781/) (2019)
- [Kvasir-SEG: A Segmented Polyp Dataset](https://mlsanity.com/paper/1911.07069/) (2019)
- [Semi-Supervised Semantic Segmentation with Cross Pseudo Supervision](https://mlsanity.com/paper/2106.01226/) (2021)
- [PraNet: Parallel Reverse Attention Network for Polyp Segmentation](https://mlsanity.com/paper/2006.11392/) (2020)
- [A Fourier-based Framework for Domain Generalization](https://mlsanity.com/paper/2105.11120/) (2021)
- [Semi-supervised Medical Image Segmentation through Dual-task Consistency](https://mlsanity.com/paper/2009.04448/) (2020)
- [Revisiting Weak-to-Strong Consistency in Semi-Supervised Semantic Segmentation](https://mlsanity.com/paper/2208.09910/) (2022)
- [FSDR: Frequency Space Domain Randomization for Domain Generalization](https://mlsanity.com/paper/2103.02370/) (2021)
- [Polyp-PVT: Polyp Segmentation with Pyramid Vision Transformers](https://mlsanity.com/paper/2108.06932/) (2021)
- [Bidirectional Copy-Paste for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2305.00673/) (2023)
- [Mutual Consistency Learning for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2109.09960/) (2021)
- [Shallow Attention Network for Polyp Segmentation](https://mlsanity.com/paper/2108.00882/) (2021)
- [Dual Student: Breaking the Limits of the Teacher in Semi-supervised Learning](https://mlsanity.com/paper/1909.01804/) (2019)
- [Combo Loss: Handling Input and Output Imbalance in Multi-Organ Segmentation](https://mlsanity.com/paper/1805.02798/) (2018)
- [UACANet: Uncertainty Augmented Context Attention for Polyp Segmentation](https://mlsanity.com/paper/2107.02368/) (2021)
- [Inconsistency-aware Uncertainty Estimation for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2110.08762/) (2021)
- [MSRF-Net: A Multi-Scale Residual Fusion Network for Biomedical Image Segmentation](https://mlsanity.com/paper/2105.07451/) (2021)
- [Adaptive Context Selection for Polyp Segmentation](https://mlsanity.com/paper/2301.04799/) (2023)
- [FCN-Transformer Feature Fusion for Polyp Segmentation](https://mlsanity.com/paper/2208.08352/) (2022)
- [Adaptive Bidirectional Displacement for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2405.00378/) (2024)
- [MEGANet: Multi-Scale Edge-Guided Attention Network for Weak Boundary Polyp Segmentation](https://mlsanity.com/paper/2309.03329/) (2023)
- [RCPS: Rectified Contrastive Pseudo Supervision for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2301.05500/) (2023)
- [Compete to Win: Enhancing Pseudo Labels for Barely-supervised Medical Image Segmentation](https://mlsanity.com/paper/2304.07519/) (2023)
- [CUTS: A Deep Learning and Topological Framework for Multigranular Unsupervised Medical Image Segmentation](https://mlsanity.com/paper/2209.11359/) (2022)
- [DyCON: Dynamic Uncertainty-aware Consistency and Contrastive Learning for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2504.04566/) (2025)

## Abstract (arXiv)

Automated polyp segmentation is essential for early diagnosis of colorectal cancer, yet developing robust models remains challenging due to limited annotated data and significant performance degradation under domain shift. Although semi-supervised learning (SSL) reduces annotation requirements, existing methods rely on generic augmentations that ignore polyp-specific structural properties, resulting in poor generalization to new imaging centers and devices. To address this, we introduce Frequency Prior Guided Matching (FPGM), a novel augmentation framework built on a key discovery: polyp edges exhibit a remarkably consistent frequency signature across diverse datasets. FPGM leverages this intrinsic regularity in a two-stage process. It first learns a domain-invariant frequency prior from the edge regions of labeled polyps. Then, it performs principled spectral perturbations on unlabeled images, aligning their amplitude spectra with this learned prior while preserving phase information to maintain structural integrity. This targeted alignment normalizes domain-specific textural variations, thereby compelling the model to learn the underlying, generalizable anatomical structure. Validated on six public datasets, FPGM establishes a new state-of-the-art against ten competing methods. It demonstrates exceptional zero-shot generalization capabilities, achieving over 10% absolute gain in Dice score in data-scarce scenarios. By significantly enhancing cross-domain robustness, FPGM presents a powerful solution for clinically deployable polyp segmentation under limited supervision.
